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个人简介
Rob Hoeben has a keen interest in development and clinical translation of viral tools for gene and stem cell therapy. He has a long-term expertise in viruses for gene therapy. Initially his work focused on retrovirus and adenovirus-derived vectors for gene therapy of hemophilia A. In parallel, he generated new cell lines for the production of adenoviruses, such as the 911 cell line for production of research grade viruses and, in collaboration with scientist at Crucell, the PER.C6 cell line for clinical grade products. Later he embraced the use of mammalian reoviruses. His lab pioneered a strategy for their genetic modification allowing the construction of a replication-competent genetically retargeted reovirus.
研究兴趣
论文共 253 篇作者统计合作学者相似作者
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CANCER GENE THERAPYno. 1 (2024): 58-68
MOLECULAR ONCOLOGYno. 5 (2024): 1245-1258
Cancer research communicationsno. 2 (2023): 325-337
Diabetologiano. 11 (2023): 2075-2086
René van Tienhoven,Maria J L Kracht,Arno R van der Slik,Sofia Thomaidou,Anouk H G Wolters, Ben N G Giepmans,Juan Pablo Romero Riojas,Michael S Nelson,Françoise Carlotti, Eelco J P de Koning,Rob C Hoeben,Arnaud Zaldumbide,
Thijs J. Janssen,Geertje van der Horst, Arjanneke F. van der Merbel,Maaike van der Mark, Martine L.M. Lamfers, Bernadette G. van den Hoogen, Sjoerd S. van der Burg, Dana A. M. Mustafa,Niven Mehra,Tilly Aalders,Nadine van Montfoort,Jack A. Schalken,
Cancer Researchno. 7_Supplement (2023): 1802-1802
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