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I have considerable experience in cancer drug discovery. Most of my career has been devoted to developing targeted therapies for cancer, specifically Antibody-Drug Conjugates (ADCs), to provide effective, but less toxic options to the patient.
I started off as a bench chemist, and during my 30+ years as a cancer researcher, I have been involved in numerous aspects of cancer drug development, starting with conception of an idea to bench chemistry, and lead optimization. Subsequently, I guided preclinical research to identify a clinical candidate, and then facilitated technology transfer for scale up synthesis for clinical trials. The culmination of one of my efforts was the FDA approval of the cancer drug Kadcyla for the treatment of breast cancer. I am one of the two inventors on the issued U.S. Patent 8,337,856 that covers the “composition of matter” of this drug.
I started off as a bench chemist, and during my 30+ years as a cancer researcher, I have been involved in numerous aspects of cancer drug development, starting with conception of an idea to bench chemistry, and lead optimization. Subsequently, I guided preclinical research to identify a clinical candidate, and then facilitated technology transfer for scale up synthesis for clinical trials. The culmination of one of my efforts was the FDA approval of the cancer drug Kadcyla for the treatment of breast cancer. I am one of the two inventors on the issued U.S. Patent 8,337,856 that covers the “composition of matter” of this drug.
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论文共 20 篇作者统计合作学者相似作者
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Jose F Ponte,Leanne Lanieri,Eshita Khera,Rassol Laleau,Olga Ab, Christopher Espelin,Neeraj Kohli, Bahar Matin,Yulius Setiady,Michael L Miller,Thomas A Keating,Ravi Chari,
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Experimental and Molecular Therapeutics (2017): 71-71
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Kathleen Whiteman, Holly Johnson,Alan Wilhelm,Michael Miller,Wei Li,Emily Reid,Katie Archer,Nathan Fishkin, Andre Dandeneau,Erin Maloney,Jan Pinkas,Ravi Chari
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