基本信息
浏览量:1
职业迁徙
个人简介
Our research activity is primarily centered on intracellular protein degradation via the ubiquitin-proteasome pathway. The ubiquitin-proteasome system is highly conserved and is the major pathway for intracellular proteolysis in all eukaryotic cells. Accordingly, ubiquitin-dependent protein degradation plays a pivotal role in the turnover of key regulatory proteins involved in a series of cellular processes, including cell cycle control, signal transduction, and protein folding. For a number of years a focus area for us has been how abnormal or misfolded proteins are targeted for degradation. To this end, we focus on genetic disorders and use yeast and mammalian cells in tissue culture as model systems, combined with a series of genetic, biochemical and molecular cell biological methods. In addition, we collaborate closely with a number of other research groups both in Denmark and abroad.
研究兴趣
论文共 114 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Lene Clausen,Vasileios Voutsinos,Matteo Cagiada,Kristoffer E. Johansson,Martin Grønbæk-Thygesen, Snehal Nariya, Rachel L. Powell, Magnus K. N. Have,Vibe H. Oestergaard,Amelie Stein,Douglas M. Fowler,Kresten Lindorff-Larsen,
Nature Communicationsno. 1 (2024): 1-17
bioRxiv (Cold Spring Harbor Laboratory) (2023)
引用0浏览0引用
0
0
Protein Scienceno. 9 (2023)
引用1浏览0引用
1
0
PROTEIN SCIENCEno. 9 (2023)
引用0浏览0引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn