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Research
Dr de Silva’s research focuses on the use of imaging (invasive intracoronary and non-invasive cross-sectional) in the diagnosis and risk stratification and evaluation of treatment of coronary artery disease. He also has an interest in hypertension management.
His work is funded by the British Heart Foundation. He currently co-supervises 2 PhD and 1 Masters student.
Clinical Trials/Registries
Dr de Silva is UK or site PI for a number of multicentre clinical trials including BLADE (ClinicalTrials.gov identifier NCT02645799); EuroCTO (ClinicalTrials.gov identifier NCT01760083); Lipid Rich Plaque (ClinicalTrials.gov identifier NCT02033694); REDUCER-1 Registry; Ivabradine Drug Utilisation Study in Select European Countries: A Multinational, Retrospective, Observational Study to Assess Effectiveness of Risk-Minimisation Measures.
Current active areas of translational and clinical research
Shear stress and atherogenesis
Biomechanical models for the prediction of advanced coronary atherosclerotic plaque development and rupture risk.
Diffusion tensor cardiac magnetic resonance for prediction of adverse left ventricular remodelling, heart failure and arrhythmic risk after myocardial infarction
Diagnosis and treatment of microvascular dysfunction.
Novel approaches to management of patients with refractory angina
New approaches to the treatment of hypertension (renal denervation, ROX)
Dr de Silva’s research focuses on the use of imaging (invasive intracoronary and non-invasive cross-sectional) in the diagnosis and risk stratification and evaluation of treatment of coronary artery disease. He also has an interest in hypertension management.
His work is funded by the British Heart Foundation. He currently co-supervises 2 PhD and 1 Masters student.
Clinical Trials/Registries
Dr de Silva is UK or site PI for a number of multicentre clinical trials including BLADE (ClinicalTrials.gov identifier NCT02645799); EuroCTO (ClinicalTrials.gov identifier NCT01760083); Lipid Rich Plaque (ClinicalTrials.gov identifier NCT02033694); REDUCER-1 Registry; Ivabradine Drug Utilisation Study in Select European Countries: A Multinational, Retrospective, Observational Study to Assess Effectiveness of Risk-Minimisation Measures.
Current active areas of translational and clinical research
Shear stress and atherogenesis
Biomechanical models for the prediction of advanced coronary atherosclerotic plaque development and rupture risk.
Diffusion tensor cardiac magnetic resonance for prediction of adverse left ventricular remodelling, heart failure and arrhythmic risk after myocardial infarction
Diagnosis and treatment of microvascular dysfunction.
Novel approaches to management of patients with refractory angina
New approaches to the treatment of hypertension (renal denervation, ROX)
研究兴趣
论文共 111 篇作者统计合作学者相似作者
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Michael J Foley, Christopher A Rajkumar,Fiyyaz Ahmed-Jushuf,Florentina A Simader, Shayna Chotai,Rachel H Pathimagaraj, Muhammad Mohsin,Ahmed Salih, Danqi Wang, Prithvi Dixit, John R Davies, Tom R Keeble,
Lancet (London, England) (2024)
Ramyah Rajakulasingam,Pedro Ferreira,Andrew Scott,Zohya Khalique,Alessia Azzu, Maria Dwornik,Miriam Conway,Emanuela Falaschetti,Kevin Cheng,Daniel Hammersley,Emily Cantor,Alexander Tindale,
Jiahao Huang,Pedro F. Ferreira,Lichao Wang,Yinzhe Wu, Angelica I. Aviles-Rivero,Carola-Bibiane Schönlieb,Andrew D. Scott,Zohya Khalique,Maria Dwornik, Ramyah Rajakulasingam,Ranil De Silva,Dudley J. Pennell,
Scientific Reportsno. 1 (2024): 1-15
Michael J Foley, Christopher A Rajkumar,Fiyyaz Ahmed-Jushuf,Florentina A Simader, Shayna Chotai,Rachel H Pathimagaraj, Muhammad Mohsin, Ahmed Salih, Danqi Wang, Prithvi Dixit,John R Davies, Tom R Keeble,
Fotios Savvopoulos,Michael C. Keeling,Daniele Carassiti, Nicholas A. Fogell,Miten B. Patel,Jarka Naser,Nuria Gavara,Ranil de Silva,Rob Krams
JOURNAL OF THE ROYAL SOCIETY INTERFACEno. 211 (2024): 20230674-20230674
Ramyah Rajakulasingam,Pedro Ferreira,Andrew Scott,Zohya Khalique,Alessia Azzu, Maria Dwornik,Miriam Conway, Emanuela Falaschetti,Kevin Cheng,Emily Cantor,Alexander Tindale, Catherine Beattie,
Michael J Foley, Christopher A Rajkumar,Fiyyaz Ahmed-Jushuf,Florentina A Simader, Shayna Chotai,Rachel H Pathimagaraj, Muhammad Mohsin,Ahmed Salih, Danqi Wang, Prithvi Dixit, John R Davies, Tom R Keeble,
Michael Tanzer,Andrew Scott,Zohya Khalique, Maria Dwornik, Ramyah Rajakulasingam,Ranil de Silva,Dudley Pennell,Pedro Ferreira,Guang Yang,Daniel Rueckert,Sonia Nielles-Vallespin
Journal of Nuclear Cardiology (2024): 101803-101803
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