基本信息
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职业迁徙
个人简介
Areas of Teaching Focus
Genetics, genomics, bioinformatics, neuroscience, stereology, data science and sharing
Areas of Research/Scholarship Focus
Virtually all disease is due to complex interactions between genetic and environmental factors. Our group at UTHSC has developed novel rodent models of disease that incorporate levels of genetic complexity that mirror most human populations. We are using these resources—the BXD family and the Hybrid Rat Diversity Panel—to build and test causal models of disease mechanisms with a special focus on diseases of aging, addiction, and neurological and psychiatric disease. To enable broad use of experimental approaches to precision health care (individualized and predictive medicine), we are also developing powerful open-source web services, such as GeneNetwork (www.genenetwork.org) to study gene function, molecular mechanisms of disease risk using linkage analysis, genome-wide association mapping, and phenome-wide association.
研究兴趣
论文共 444 篇作者统计合作学者相似作者
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Robyn L. Ball, Molly A. Bogue,Hongping Liang,Anuj Srivastava,David G. Ashbrook,Anna Lamoureux, Matthew W. Gerring, Alexander S. Hatoum, Matthew J. Kim,Hao He,Jake Emerson, Alexander K. Berger,
GENOME RESEARCHno. 1 (2024): 145-159
Robyn L Ball,Molly A Bogue,Hongping Liang,Anuj Srivastava,David G Ashbrook,Anna Lamoureux, Matthew W Gerring, Alexander S Hatoum, Matthew J Kim,Hao He,Jake Emerson, Alexander K Berger,
Genome researchno. 1 (2024): 145-159
Delphine Larivière,Linelle Abueg,Nadolina Brajuka,Cristóbal Gallardo-Alba,Bjorn Grüning,Byung June Ko, Alex Ostrovsky,Marc Palmada-Flores, Brandon D. Pickett, Keon Rabbani,Agostinho Antunes,Jennifer R. Balacco,
Harrison Mansour, Ryan Azrak,James J Cook,Kathryn J Hornburg,Yi Qi,Yuqi Tian,Robert W Williams,Fang-Cheng Yeh,Leonard E White,G Allan Johnson
bioRxiv : the preprint server for biology (2024)
Samson Eugin Simon, Boston William Simmons, Minjeong Kim, Sydney Clarice Joseph,Emily Korba, Sandesh J Marathe,Margaret Sue Bohm, Sidharth Mahajan,Casey Bohl,Robert Read,Jeremiah Holt,Neil Hayes,
biorxiv(2024)
Ling Li,Zhiping Wu,Andrea Guarracino,Flavia Villani, Deihui Kong,Ariana Mancieri, Aijun Zhang,Laura M Saba,Hao Chen,Hana Brozka,Karel Vales, Anna N Senko,
biorxiv(2024)
Advances in experimental medicine and biology (2023): 371-376
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bioRxiv : the preprint server for biology (2023)
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCEno. 8 (2023)
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bioRxiv : the preprint server for biology (2023)
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