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We use an interdisciplinary research approach to understand the roles of peptides as messengers and regulators of critical physiological processes. We collaborate with our colleagues at The University of Michigan Medical School to translate our research from basic science to applied human health.
Our research is focused on RFamide peptides, a group of structurally-related brain-gut peptides conserved in all animals. Activities and tissue distribution data suggest RFamides are involved in regulating cardiovascular parameters; however, the underlying mechanisms and function of a RFamide are yet to be elucidated. Delineating molecular mechanisms involved in how a peptide impacts human cardiovascular physiology positions us to identify target molecules for drug development and therapy.
Our research is focused on RFamide peptides, a group of structurally-related brain-gut peptides conserved in all animals. Activities and tissue distribution data suggest RFamides are involved in regulating cardiovascular parameters; however, the underlying mechanisms and function of a RFamide are yet to be elucidated. Delineating molecular mechanisms involved in how a peptide impacts human cardiovascular physiology positions us to identify target molecules for drug development and therapy.
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