Robert Furst

基本信息

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职业迁徙

个人简介

My group works in the field of Pharmaceutical Biology and focusses on the identification and characterization of biogenic compounds with an action on the human endothelium in order to fight inflammation and cancer.

研究兴趣

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Inhibition of DYRK1B BY C81 Impedes Inflammatory Processes in Leukocytes by Reducing STAT3 Activity

Sarah Ciurus,Mohammed A. F. Elewa,Megan A. Palmer,Anne Wolf, Mandy Hector,Dominik C. Fuhrmann,Dominique Thomas,Robert Gurke,Martin P. Schwalm, Lena Berger, Thomas J. Zech,Luisa D. Burgers,Rolf Marschalek,Gerd Geisslinger,Stefan Knapp,Thomas Langmann,Franz Bracher,Andreas Weigert,Robert Fürst

Cellular and Molecular Life Sciencesno. 1 (2025): 1-25

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(Homo-)Harringtonine Prevents Endothelial Inflammation Through IRF-1 Dependent Downregulation of VCAM1 Mrna Expression and Inhibition of Cell Adhesion Molecule Protein Biosynthesis

Luisa D. Burgers, Sarah Ciurus,Patrick Engel,Silvia Kuntschar,Rebecca Raue,Anastasiia Kiprina, Tobias Primke,Tobias Schmid,Andreas Weigert,Achim Schmidtko,Robert Fuerst

Biomedicine & Pharmacotherapy (2024): 116907-116907

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Venomics of the Milos Viper (macrovipera Schweizeri)

Lennart Schulte,Maik Damm,Ignazio Avella,Lilien Uhrig,Pelin Erkoc,Susanne Schiffmann,Robert Fuerst,Thomas Timm,Guenter Lochnit,Andreas Vilcinskas,Tim Lueddecke

Toxicon（2024）

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Bioactivity Profiling of Novel Pseudoscorpion Toxins with Antimicrobial Activity: from Biological Considerations to Future Anti-Infective Applications

Pelin Erkoc,Susanne Schiffmann,Thomas Ulshofer,Marina Henke,Michael Marner,Jonas Kramer,Reinhard Predel,Till F. Schaberle,Sabine Hurka,Ludwig Dersch,Andreas Vilcinskas,Robert Furst,Tim Luddecke

Toxicon (2024): 107966-107966

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Diversely Evolved Xibalbin Variants from Remipede Venom Inhibit Potassium Channels and Activate PKA-II and Erk1/2 Signaling

Ernesto Lopes Pinheiro-Junior, Ehsan Alirahimi,Steve Peigneur,Jörg Isensee,Susanne Schiffmann,Pelin Erkoc,Robert Fürst,Andreas Vilcinskas, Tobias Sennoner,Ivan Koludarov,Benjamin-Florian Hempel,Jan Tytgat,Tim Hucho,Björn M. von Reumont

BMC BIOLOGY（2024）

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STRUCTURE-BASED DESIGN OF PROTACS FOR THE DEGRADATION OF SOLUBLE EPOXIDE HYDROLASE

Julia Schoenfeld,Steffen Brunst, Ludmila Ciomirtan, Nick Liebisch,Adarsh Kumar, Johanna Ehrler, Lukas Wintermeier,Jan Heering, Astrid Brueggerhof,Lilia Weizel,Astrid Kahnt,Manfred Schubert-Zsilavecz,Stefan Knapp,Robert Fuerst,Eugen Proschak,Kerstin Hiesinger

biorxiv（2024）

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Determining the Pharmacological Potential and Biological Role of Linear Pseudoscorpion Toxins Via Functional Profiling

Pelin Erkoc,Susanne Schiffmann,Thomas Ulshoefer,Marina Henke,Michael Marner,Jonas Kraemer,Reinhard Predel,Till F. Schaeberle,Sabine Hurka,Ludwig Dersch,Andreas Vilcinskas,Robert Fuerst,Tim Lueddecke

iScienceno. 7 (2024): 110209-110209

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2-Desaza-annomontine (C81) Impedes Angiogenesis Through Reduced VEGFR2 Expression Derived from Inhibition of CDC2-like Kinases

T. J. Zech, A. Wolf, M. Hector,I. Bischoff-Kont,G. M. Krishnathas, S. Kuntschar,T. Schmid,F. Bracher,T. Langmann,R. Fürst

ANGIOGENESISno. 2 (2024): 245-272

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HPLC- and NMR-Based Chemical Profiling, Wound-Healing Potential, Anti-Inflammatory and Antibacterial Activities of Satureja Pilosa (lamiaceae), a Neglected Medicinal–Aromatic Herb

Christina Panagiotidou,Luisa D. Burgers,Christina Tsadila,Chara Almpani,Nikos Krigas,Dimitris Mossialos,Michail Christou Rallis,Robert Fuerst,Anastasia Karioti

PLANTS-BASELno. 24 (2023)

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The Microtubule-Targeting Agent Pretubulysin Impairs the Inflammatory Response in Endothelial Cells by a JNK-Dependent Deregulation of the Histone Acetyltransferase Brd4

Tobias F. Primke,Rebecca Ingelfinger,Mohammed A. F. Elewa,Igor Macinkovic,Andreas Weigert,Matthias P. Fabritius,Christoph A. Reichel,Angelika Ullrich,Uli Kazmaier,Luisa D. Burgers,Robert Fuerst

CELLSno. 16 (2023)

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