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The group develops, tests and optimises selective cancer treatments in vitro and in vivo, using novel antibody and vascular targeted therapies as either single or combined strategies (Fig 1).
We have increasingly concentrated on the impact of the tumour microenvironment on therapy and vice versa, and a major part of our research concerns the development of systems for overcoming or exploiting tumour heterogeneity, in order to optimise future clinical trials. The most intensively studied tumour is colorectal carcinoma, but many of the other common tumours are also under investigation.
We have increasingly concentrated on the impact of the tumour microenvironment on therapy and vice versa, and a major part of our research concerns the development of systems for overcoming or exploiting tumour heterogeneity, in order to optimise future clinical trials. The most intensively studied tumour is colorectal carcinoma, but many of the other common tumours are also under investigation.
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NATURE BIOMEDICAL ENGINEERINGno. 10 (2018): 773-787
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