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For nearly four decades, Bob was the embodiment of translational research, using knowledge gleaned from his passionate clinical practice to inform basic research and develop therapies to be tested back in the clinic. Among his work with the most clinical impact was his use of cyclosporine, an immunosuppressant drug often administered to prevent rejection in organ transplantation, to treat uveitis, the inflammation of the uvea and surrounding areas in the eye. Bob was the first to take the approach of using an immunosuppressant compound for uveitis, which many at the time thought was unlikely to be effective. Yet cyclosporine has become a standard treatment for uveitis, sparing many patients from the long-term use of steroids to control this condition.
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Zhuqing Li,Sankaranarayana P. Mahesh, De Fen Shen,Baoying Liu, Willie O. Siu,Frank S. Hwang, Qing-Chen Wang,Chi-Chao Chan,Ira Pastan,Robert B. Nussenblatt
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Zhuqing Li,Sankaranarayana P. Mahesh, De Fen Shen,Baoying Liu, Willie O. Siu,Frank S. Hwang, Qing-Chen Wang,Chi-Chao Chan,Ira Pastan,Robert B. Nussenblatt
crossref(2023)
Zhuqing Li,Sankaranarayana P. Mahesh, De Fen Shen,Baoying Liu, Willie O. Siu,Frank S. Hwang, Qing-Chen Wang,Chi-Chao Chan,Ira Pastan,Robert B. Nussenblatt
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