DeKemp's interest is in medical imaging physics and engineering, including Positron Emission Tomography (PET), single photon emission computed tomography (SPECT), X-ray computed tomography (CT), X-ray angiography, and multimodality image fusion.
He is developing innovative tracer kinetic and statistical parametric methods for serial imaging of PET blood flow and metabolism, and 3-D fusion imaging of coronary angiography and myocardial perfusion. His pioneering research in singles transmission for 3-D PET has greatly improved PET attenuation correction and is now a commercial standard for 3-D PET in the world.