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Associate Professor Dong’s team is investigating the mechanism of, and the way to prevent, cancer recurrence. Cancers are made up of both actively dividing and "resting" cancer cells. These “resting” (quiescent) cancer cells are thought to be central to recurrence,following elimination of cycling cells by chemo- or radio-therapies. With the significant increase in overall cancer survival time, how to prevent cancer recurrence has become a critically important issue. Based on the principle of efficacy, no toxicity and low cost, the team has examined the potential of compounds isolated from edible plant, citrus peel extract, and traditional Chinese medicine in blocking the transition from the “resting” to actively dividing cancer cells.
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Acta Materia Medicano. 1 (2022): 56-71
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