My research focuses on the development of innovative data-driven technologies of rational antibody design, to obtain antibodies against targets that have been challenging to access using conventional approaches. At the Centre for Misfolding Diseases, at the University of Cambridge I apply these technologies to generate novel opportunities for research, diagnostics, and eventually treatment of neurodegenerative disorders, such as Alzheimer's or Parkinson's disease. Through this work we established numerous collaborations and industrial partnerships, whose outcomes are beginning to demonstrate that computational approaches can be applied alongside established procedures to streamline antibody development, and to offer time- and cost-effective novel alternatives.