基本信息
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职业迁徙
个人简介
Mission
BIOGRAPHY
RESEARCH TOPICS (more than 400 publications in referred journals)
Asymmetric Synthesis of Natural Products and Analogs of Biological Interest (anti-cancer, antiviral agents, antibiotics). Actual targets: Spongistatins (anti-cancer), Aptotolidin (anti-cancer), oxopolyene RK-397 (antibiotic), Ryfamycins (antibiotics, antifungals, Erythronolides (antibiotics).
Glycomimetics as New Tools for Biology and Medicine (glycomics, cell/cell communication, cell/pathogen communication: glycosidase and glycosyltransferase inhibitors, non-hydrolysable sugar epitopes). New inhibitors of α-mannosidases and α-glucosidases as potential anti-cancer and anti-HIV agents. Artificial vaccines against cancer, synthesis of C-linked disaccharides analogs of the T-epitopes.
New Scaffolds for Biomolecules, for New Materials (polyfunctional systems for combinatorial chemistry, multicomponent synthesis).
New Organic Chemistry of Sulfur Dioxide (new C-C bond forming reactions, synthesis of polyketides and polypropionates, new reagents, new organic catalysts for hole-catalysed reactions).
BIOGRAPHY
RESEARCH TOPICS (more than 400 publications in referred journals)
Asymmetric Synthesis of Natural Products and Analogs of Biological Interest (anti-cancer, antiviral agents, antibiotics). Actual targets: Spongistatins (anti-cancer), Aptotolidin (anti-cancer), oxopolyene RK-397 (antibiotic), Ryfamycins (antibiotics, antifungals, Erythronolides (antibiotics).
Glycomimetics as New Tools for Biology and Medicine (glycomics, cell/cell communication, cell/pathogen communication: glycosidase and glycosyltransferase inhibitors, non-hydrolysable sugar epitopes). New inhibitors of α-mannosidases and α-glucosidases as potential anti-cancer and anti-HIV agents. Artificial vaccines against cancer, synthesis of C-linked disaccharides analogs of the T-epitopes.
New Scaffolds for Biomolecules, for New Materials (polyfunctional systems for combinatorial chemistry, multicomponent synthesis).
New Organic Chemistry of Sulfur Dioxide (new C-C bond forming reactions, synthesis of polyketides and polypropionates, new reagents, new organic catalysts for hole-catalysed reactions).
研究兴趣
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