Philip M. Sher

Bristol-Myers Squibb Pharmaceutical Research Institute

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论文共 35 篇作者统计合作学者相似作者

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Utilization of an Active Site Mutant Receptor for the Identification of Potent and Selective Atypical 5-HT_2C Receptor Agonists

Joseph Carpenter,Ying Wang,Gang Wu,Jianxin Feng,Xiang-Yang Ye,Christian L. Morales,Matthias Broekema,Karen A. Rossi,Keith J. Miller,Brian J. Murphy,Ginger Wu,Sarah E. Malmstrom,Anthony V. Azzara,Philip M. Sher,John M. Fevig,Andrew Alt,Robert L. Bertekap,Mary Jane Cullen, Timothy M. Harper,Kimberly Foster,Emily Luk,Qian Xiang,Mary F. Grubb,Jeffrey A. Robl,Dean A. Wacker

Journal of Medicinal Chemistry（2017）

引用0浏览0引用

Utilization of an active site mutant receptor for the identification of potent and selective atypical 5-HT2C receptor agonists

Joseph Carpenter,Ying Wang,Gang Wu,Jianxin Feng,Xiang-Yang Ye,Christian L Morales,Matthias Broekema,Karen A Rossi,Keith J Miller,Brian J Murphy,Ginger Wu,Sarah E Malmstrom,Anthony V Azzara,Philip M Sher,John M Fevig,Andrew Alt,Robert L Bertekap,Mary Jane Cullen, Timothy M Harper,Kimberly Foster,Emily Luk,Qian Xiang,Mary F Grubb,Jeffrey A Robl,Dean A Wacker

JOURNAL OF MEDICINAL CHEMISTRY（2017）

引用11浏览0WOS引用

Reductions in Log P Improved Protein Binding and Clearance Predictions Enabling the Prospective Design of Cannabinoid Receptor (CB1) Antagonists with Desired Pharmacokinetic Properties

Bruce A. Ellsworth,Philip M. Sher,Ximao Wu,Gang Wu,Richard B. Sulsky,Zhengxiang Gu,Natesan Murugesan,Yeheng Zhu,Guixue Yu,Doree F. Sitkoff,Kenneth E. Carlson,Liya Kang,Yifan Yang,Ning Lee,Rose A. Baska,William J. Keim,Mary Jane Cullen,Anthony V. Azzara,Eva Zuvich,Michael A. Thomas,Kenneth W. Rohrbach,James J. Devenny,Helen E. Godonis,Susan J. Harvey,Brian J. Murphy,Gerry G. Everlof,Paul I. Stetsko,Olafur Gudmundsson,Susan Johnghar,Asoka Ranasinghe,Kamelia Behnia,Mary Ann Pelleymounter,William R. Ewing

Journal of Medicinal Chemistry（2013）

引用10浏览0WOS引用

DIAMINOCYCLOHEXANE COMPOUNDS AND USES THEREOF

William R Ewing,Yeheng Zhu,Chongqing Sun,Yanting Huang, Maheswaran Sivasamban Karatholuvhu,Scott A Bolton,Laxman Pasunoori, Sunil Kumar Mandal,Philip M Sher

mag（2013）

引用24浏览0引用

Strategies To Reduce Log P To Improve Pharmaceutical Properties Of A Series Of Cb1 Receptor Antagonists

Ximao Wu,Bruce A. Ellsworth,Guixue Yu,Amarendra Mikkilineni,Zhengxiang Gu,Natesan Murugesan,Yanting Huang,Chongqing Sun,Annapurna Pendri,Philip M. Sher,Gang Wu,Yeheng Zhu,Doree F. Sitkoff,Liya Kang,Yifan Yang,Ning Lee,Mary Jane Cullen,William J. Keim,Mary Ann Pelleymounter,Paul I. Stetsko,Gerry G. Everlof,Olafur S. Gudmunsson,Susan Johnghar,Steven T. Wu,Asoka Ranasinghe,Wenying Li,Kamelia Behnia,Kenneth E. Carlson,William R. Ewing

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2012）

引用0浏览0引用

Design, Synthesis And Sar Of Triazolopyridazine Based Cannabinoid-1 Receptor Antagonists

Yanting Huang,Chongqing Sun,Guixue Yu,Amarendra Mikkilineni,Ximao Wu,Zhengxiang Gu,Natesan Murugesan,Bruce A. Ellsworth,Annapurna Pendri,Philip Sher,Gang Wu,Yeheng Zhu,Doree Sitkoff,Liya Kang,Yifan Yang,Ning Lee,Mary Jane Cullen,William Keim,Mary Ann Pelleymounter,Paul Stetsko,Gerry Everlof,Olafur Gudmunsson,Susan Johnghar,Steven Wu,Asoka Ranasinhe,Wenying Li,Kamelia Behnia,Kenneth E. Carlson,William R. Ewing

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (2011)

引用0浏览0引用

Discovery Of Bms-812204, A Cannabinoid Receptor (Cb1) Antagonist, Via Reductions In Log P In The Series To Balance Volume Of Distribution And Clearance

Bruce A. Ellsworth,Ximao Wu,Philip M. Sher,Gang Wu,Amarendra Mikkilineni,Zhengxiang Gu,Natesan Murugesan,Yeheng Zhu,Guixue Yu,Doree Sitkoff,Kenneth Carlson,Liya Kang,Yifan Yang,Ning Lee,Roseann Baska,Qi Huang,William Keim,Mary Jane Cullen,Eva Zuvich,Michael Thomas,Kenneth W. Rohrbach,James J. Devenny,Helen Godonis,Susan Harvey,Brian J. Murphy, Gerry Everloff,Paul Stetsko,Olafur Gudmundsson,Susan Johnghar,Asoka Ranasinghe,Kamelia Behnia,Maryann Pelleymounter,William R. Ewing

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2009）

引用1浏览0引用

Triazolopyridazines (Tzp) As Cannabinoid-1 Receptor Antagonists: The Generation Of Multiple Novel Tzp Chemotypes Via Conformationally Constraining A Pyrazine Carboxamide Lead

Chongqing Sun,Yanting Huang,Guixue Yu,Amarendra Mikkilineni,Ximao Wu,Zhengxiang Gu,Natesan Murugesan,Bruce A. Ellsworth,Philip Sher,Annapurna Pendri,Gang Wu,Yeheng Zhu,Samuel Gerritz,Doree Sitkoff,Liya Kang,Yifan Yang,Rose Ann Baska,Ning Lee,Mary Jane Cullen,William Keim,Mary Ann Pelleymounter,Paul Stetsko,Gerry Everlof,Susan Johnghar,Steven Wu,Asoka Ranasinhe,Wenying Li,Kamelia Behnia,Kenneth E. Carlson,William R. Ewing

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2009）

引用0浏览0引用

Aglycone Exploration of C-arylglucoside Inhibitors of Renal Sodium-Dependent Glucose Transporter SGLT2

Bruce A. Ellsworth,Wei Meng,Manorama Patel,Ravindar N. Girotra,Gang Wu,Philip M. Sher,Deborah L. Hagan,Mary T. Obermeier,William G. Humphreys,James G. Robertson,Aiying Wang,Songping Han,Thomas L. Waldron,Nathan N. Morgan,Jean M. Whaley,William N. Washburn

Bioorganic & Medicinal Chemistry Letters（2008）

引用71浏览0WOS引用

Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (sglt2) Inhibitor for the Treatment of Type 2 Diabetes

Wei Meng,Bruce A. Ellsworth,Alexandra A. Nirschl,Peggy J. McCann,Manorama Patel,Ravindar N. Girotra,Gang Wu,Philip M. Sher,Eamonn P. Morrison,Scott A. Biller,Robert Zahler,Prashant P. Deshpande,Annie Pullockaran,Deborah L. Hagan,Nathan Morgan,Joseph R. Taylor,Mary T. Obermeier,William G. Humphreys,Ashish Khanna,Lorell Discenza,James G. Robertson,Aiying Wang, Songping Hang,John R. Wetterau,Evan B. Janovitz,Oliver P. Flint,Jean M. Whaley,William N. Washburn

JOURNAL OF MEDICINAL CHEMISTRY（2008）

引用669浏览0WOS引用

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作者统计

#Papers: 35

#Citation: 1802

H-Index: 23

G-Index: 27

Sociability: 5

Diversity: 1

Activity: 0

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