Phang-Lang Chen

Department of Molecular Medicine and Institute of Biotechnology|University of Texas Health Science Center at San Antonio

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Papers47 papers

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Aberrant DNA damage response and DNA repair pathway in high glucose conditions

Amy Zhong, Melissa Chang, Theresa Yu, Raymond Gau, Daniel J Riley,Yumay Chen,Phang-Lang Chen

Journal of cancer research updates, no. 3 (2018): 64-74

WOSBibtex

Pharmaceutical compositions containing an indoyl isoquinoline containing compound and uses thereof

Wenhwa Lee,Phanglang Chen,Longen Zhou, Jiewen Zhu

(2015)

Bibtex

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage

Paul A. Townsend,Mark S. Cragg,Sean M. Davidson,James McCormick,Sean Barry,Kevin M. Lawrence,Richard A. Knight,Michael Hubank,Phang-Lang Chen,David S. Latchman,Anastasis Stephanou

Journal of cell science, no. 5 (2015): 1064-1064

Cited by73WOSBibtex

RESEARCH Open Access Mutation of NIMA-related kinase 1 (NEK1) leads to chromosome instability

Yumay Chen,Chifen Chen, H Chiang,Michelle Pena,Rosaria Polci, Y L Wei,Robert A Edwards,Donna E Hansel,Phanglang Chen,Daniel J Riley

(2013)

Bibtex

A novel small molecule RAD51 inactivator overcomes imatinib-resistance in chronic myeloid leukaemia: RAD51 inactivator overcomes imatinib-resistance

Jiewen Zhu, Xiaoqin Lin,Erin M Goldblatt,Ravi Bhatia,A Richard Chamberlin,Wenhwa Lee,Phanglang Chen,Guideng Li,Xiaolong Qiu,Chifen Chen,Heiko Konig, Chunmei Hu

Embo Molecular Medicine, (2013)

Bibtex

Mutation of NIMA-related kinase 1 (NEK1) leads to chromosome instability

Yumay Chen,Chi-Fen Chen,Huai-Chin Chiang,Michelle Pena,Rosaria Polci,Randy L Wei,Robert A Edwards,Donna E Hansel,Phang-Lang Chen,Daniel J Riley

Molecular cancer, no. 1 (2011): 5-5

Cited by90WOSBibtex

Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues

Xiao-Long Qiu,Guideng Li,Guikai Wu,Jiewen Zhu,Longen Zhou,Phang-Lang Chen,A Richard Chamberlin,Wen-Hwa Lee

Journal of medicinal chemistry, no. 6 (2009): 1757-1767

Cited by34WOSBibtex

Compositions and Methods Related to RAD51 Inactivation in the Treatment of Neoplastic Diseases, and Especially CML

Wenhwa Lee,Phanglang Chen, Longen Zhou, Jiewen Zhu

(2009)

Cited by3Bibtex

Structural requirements of chromokinesin Kif4A for its proper function in mitosis

Guikai Wu,Phang-Lang Chen

Biochemical and Biophysical Research Communications, no. 3 (2008): 454-458

Cited by5WOSEIBibtex

Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry

Lei Fang,Xiaorong Wang,Kosj Yamoah,Phang-lang Chen,Zhen-Qiang Pan,Lan Huang

Journal of proteome research, no. 11 (2008): 4914-4925

Cited by39WOSBibtex

Small Molecules Targeting Rad51 Recombinase Synergize with Imatinib and Overcome Imatinib-Resistance in CML

Longen Zhou,Jiewen Zhu,Heiko Konig,Xiaoqin Lin,Ravi Bhatia,A. Richard Chamberlin,Phang Lang Chen,Wen-Hwa Lee

Blood, no. 11 (2007): 466-466

Bibtex

Brca1 heterozygous mice have shortened life span and are prone to ovarian tumorigenesis with haploinsufficiency upon ionizing irradiation

Y-M Jeng,S Cai-Ng,A Li, Shuichi Furuta,H Chew,P-L Chen,E-Y-H Lee,W-H Lee

Oncogene, no. 42 (2007): 6160-6166

Cited by22WOSNATUREBibtex

Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature

Saori Furuta,Ju-Ming Wang,Shuanzeng Wei,Yung-Ming Jeng,Xianzhi Jiang,Bingnan Gu,Phang-Lang Chen,Eva Y-H P Lee,Wen-Hwa Lee

Cancer Cell, no. 1 (2006): 13-24

Cited by90WOSEIBibtex

Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency

Phang-Lang Chen,Feng Liu,Suna Cai,Xiaoqin Lin,Aihua Li,Yumay Chen,Bingnan Gu,Eva Y-H P Lee,Wen-Hwa Lee

Molecular and cellular biology, no. 9 (2005): 3535-3542

Cited by112WOSBibtex

Depletion of BRCA1 impairs differentiation but enhances proliferation of mammary epithelial cells

Saori Furuta,Xianzhi Jiang,Bingnan Gu,Eric Cheng,Phang-Lang Chen,Wen-Hwa Lee

Proceedings of the National Academy of Sciences of the United States of America, no. 26 (2005): 9176-9181

Cited by146WOSBibtex

NFBD1/Mdc1 mediates ATR-dependent DNA damage response

Aimin Peng,Phang-Lang Chen

Cancer research, no. 4 (2005): 1158-1163

Cited by19WOSBibtex

Rosaria Polci,Aimin Peng,Phang-Lang Chen,Daniel J Riley,Yumay Chen

Cancer research, no. 24 (2004): 8800-8803

Cited by59WOSBibtex

Assembly of functional ALT-associated promyelocytic leukemia bodies requires Nijmegen Breakage Syndrome 1

Guikai Wu,Xianzhi Jiang,Wen-Hwa Lee,Phang-Lang Chen

Cancer research, no. 10 (2003): 2589-2595

Cited by131WOSBibtex

Cell lineage-specific effects associated with multiple deficiencies of tumor susceptibility genes in Msh2(-/-)Rb(+/-) mice

Alexander Yu Nikitin,Chia-Yang Liu,Andrea Flesken-Nikitin,Chi-Fen Chen,Phang-Lang Chen,Wen-Hwa Lee

Cancer research, no. 18 (2002): 5134-5138

Cited by12WOSBibtex

Deficient nonhomologous end-joining activity in cell-free extracts from Brca1-null fibroblasts

Qing Zhong,Thomas G Boyer,Phang-Lang Chen,Wen-Hwa Lee

Cancer research, no. 14 (2002): 3966-3970

Cited by128WOSBibtex

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