Major Areas of Research Pathophysiology and treatment of neuroinflammatory syndromes in refractory fungal infections. Role of RNA biology in susceptibility to human fungal disease Granulocyte-monocyte colony stimulating factor (GMCSF) signaling in fungal susceptibility Fungal genetic studies of clinical outcome of Cryptococcus in AIDS and solid organ transplant recipients Genetic susceptibility to bloodstream infections by Candida albicans International Studies: Use of orally available amphotericin B lipid nano-crystals for treatment of HIV-associated cryptococcal meningitis (Uganda and Ethiopia)