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Cancer is caused by increased activity of growth-promoting genes and decreased activity of growth-inhibitory genes. These genes produce proteins that can be targeted by specific drugs. Our lab works on the molecular mechanisms of the cancer-specific changes in the regulation of cell growth and proliferation. We then apply the new knowledge to the identification of small chemical inhibitor compounds and of novel biological molecules with the goal of developing these into cancer therapies.
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Biochimica et biophysica acta. Reviews on cancerno. 5 (2023): 188947-188947
Jing Yuan,Pramod P. Mehta, Min-Jean Yin, Shaoxian Sun, Aihua Zou,Jeffrey Chen,Kristina Rafidi,Zheng Feng, Jeffrey Nickel, Jon Engebretsen,Jill Hallin,Alessandra Blasina,
crossref(2023)
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAno. 46 (2022)
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Cancer Researchno. 12_Supplement (2022): 671-671
Cancer Researchno. 12_Supplement (2022): 1535-1535
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