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Peter Vangheluwe, PhD’s research focuses on lysosomal transport systems that are implicated in Parkinson’s disease (PD) to understand the role of lysosomal dysfunction in PD. He’s appointed as Associate Professor at KU Leuven in Belgium, and is head of the Laboratory of Cellular Transport Systems. Using biochemical and molecular cell biology approaches, he characterizes new P-type transport ATPases that regulate ion homeostasis and lipid distribution in the cell. His team discovered the function of two orphan transporters that are genetically implicated in PD. He described that ATP13A2/PARK9 works as a lysosomal polyamine transporter, and that ATP10B operates as a lysosomal glucosylceramide exporter. These breakthroughs provide new insights into the molecular mechanisms of PD, and fuel a drug discovery pipeline for lysosomal transport modulators that runs together with pharmaceutical companies. He published >60 peer-reviewed publications and received two awards by the Queen Elisabeth Foundation for Neurosciences.
研究兴趣
论文共 150 篇作者统计合作学者相似作者
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Bin Liu, Mujahid Azfar, Ekaterina Legchenko,James A West,Shaun Martin,Chris Van den Haute,Veerle Baekelandt,John Wharton,Luke Howard,Martin R Wilkins,Peter Vangheluwe,Nicholas W Morrell,
Cardiovascular research (2024)
Aysha M Bhojwani-Cabrera, Alicia Bautista-García,Veronika E Neubrand, Francisco A Membrive-Jiménez,Mattia Bramini,David Martin-Oliva,Miguel A Cuadros,José Luis Marín-Teva,Julio Navascués,Peter Vangheluwe,M Rosario Sepúlveda
Glia (2024)
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCHno. 1 (2024)
Aysha M. Bhojwani‐Cabrera, Alicia Bautista‐García,Veronika E. Neubrand, Francisco A. Membrive‐Jiménez,Mattia Bramini,David Martin‐Oliva,Miguel A. Cuadros,José Luis Marín‐Teva,Julio Navascués,Peter Vangheluwe,M. Rosario Sepúlveda
Glia (2024)
Mujahid Azfar, Weiman Gao,Chris Van den Haute,Lin Xiao,Mawar Karsa,Ruby Pandher, Emma Ronca,Angelika Bongers, Ayu Karsa, Dayna Spurling, Xinyi Guo,Chelsea Mayoh,
biorxiv(2024)
Biochimica et biophysica acta. Molecular cell researchno. 1 (2024): 119612-119612
Mark Ainsley Colijn,Stephanie Vrijsen, Ping Yee (Billie) Au, Rania Abu el Asrar,Marine Houdou,Chris Van den Haute,Justyna Sarna, Greg Montgomery,Peter Vangheluwe
medrxiv(2024)
E. Pierantozzi, L. Raucci, S. Buonocore, E. M. Rubino, Q. Ding, A. Laurino, F. Fiore, M. Soldaini, J. Chen,D. Rossi,P. Vangheluwe,H. Chen,
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