Peter Loppnau - Struct Genom Consortium, Univ Toronto

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Papers共 79 篇Author StatisticsCo-AuthorSimilar Experts

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Identification of Direct-acting Nsp2 Helicase Inhibitors with Anti-alphaviral Activity

Muthu Ramalingam Bose, John D. Sears, Kacey M. Talbot, Yuan-Wei Norman Su,Scott Houliston, Mohammed Anwar Hossain, Zachary W. Davis-Gilbert, Chunqing Zhao, Hans J. Oh,Peter J. Brown, Marcia K. Sanders, Stella R. Moorman, Durbadal Ojha, Jane E. Burdick, Isabella Law, Noah L. Morales, Sabian A. Martinez,Peter Loppnau, Julia Garcia Perez, Adam M. Drobish,Thomas E. Morrison, Zachary J. Streblow,Daniel N. Streblow,Cheryl H. Arrowsmith,Ava Vargason,Rafael M. Counago, Levon Halabelian,Jamie J. Arnold,Craig E. Cameron,Nathaniel J. Moorman,Mark T. Heise,Timothy M. Willson

biorxiv（2025）

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A Live Cell BRET Probe to Quantify PRMT5-MTA Uncompetitive Target Engagement

Elisabeth Rothweiler,Ani Michaud,Jakub Stefaniak, Usha Singh, James Vasta, Michael Beck,Jennifer Ward,Catherine Rogers,Esra Balıkçı, Jeppe Tranberg-Jensen, Jesper Hansen,Peter Loppnau,Paul Brennan, Peter Tonge,Matthew Robers,Kilian Huber

crossref（2025）

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Identification of Inhibitors of Chikungunya Virus Nsp2 ATPase

Hernan Navarro, John E Scott, Ginger R Smith,Pegah Ghiabi,Elisa Gibson,Peter Loppnau,Rachel J Harding,Mohammad Anwar Hossain, Muthu Ramalingam Bose,Kenneth H Pearce, Eric M Merten,Timothy M Willson,Peter J Brown

bioRxiv the preprint server for biology (2025)

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Active Learning Guided Hit Optimization for the Leucine-Rich Repeat Kinase 2 WDR Domain Based on in Silico Ligand Binding Affinities

Journal of chemical information and modelingno. 11 (2025): 5706-5717

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ABHD2 Activity is Not Required for the Non-Genomic Action of Progesterone on Human Sperm

Oliver Arnolds, Eve M Carter, Madison Edwards,Edvard Wigren,Evert Homan, Pauline Ribera, Kirsty Bentley, Martin Haraldsson, Nmesoma Theo-Emegano,Peter Loppnau,Magdalena M Szewczyk, Michelle A Cao,Dalia Barsyte-Lovejoy, Karen Vester, Anna Thrun, Alexandra Amaral, Ralf Lesche, Jens Münchow, W. Felix Zhu, Louisa Temme,Christoph Brenker,Timo Strünker,Michael Sundström,Matthew H Todd,Aled M Edwards,Claudia Tredup, Opher Gileadi

biorxiv（2024）

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Probing the CRL4DCAF12 Interactions with MAGEA3 and CCT5 Di-Glu C-terminal Degrons

Germanna Lima Righetto,Yanting Yin,David M. Duda,Victoria Vu,Magdalena M. Szewczyk,Hong Zeng,Yanjun Li,Peter Loppnau, Tony Mei, Yen-Yen Li,Alma Seitova, Aaron N. Patrick,Jean-Francois Brazeau,Charu Chaudhry,Dalia Barsyte-Lovejoy,Vijayaratnam Santhakumar,Levon Halabelian

PNAS Nexusno. 4 (2024)

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A Resource to Enable Chemical Biology and Drug Discovery of WDR Proteins

Suzanne Ackloo,Fengling Li,Magda Szewczyk,Almagul Seitova,Peter Loppnau,Hong Zeng,Jin Xu,Shabbir Ahmad, Yelena A Arnautova, AJ Baghaie,Serap Beldar,Albina Bolotokova,Paolo A Centrella,Irene Chau,Matthew A Clark,John W Cuozzo, Saba Dehghani-Tafti,Jeremy S Disch,Aiping Dong, Antoine Dumas,Jianwen A. Feng,Pegah Ghiabi,Elisa Gibson,Justin Gilmer,Brian Goldman,Stuart R Green,Marie-Aude Guié,John P Guilinger,Nathan Harms, Oleksandra Herasymenko,Scott Houliston,Ashley Hutchinson,Steven Kearnes,Anthony D Keefe,Serah W Kimani,Trevor Kramer, Maria Kutera, Haejin A Kwak,Cristina Lento,Yanjun Li, Jenny Liu,Joachim Loup,Raquel AC Machado,Christopher J Mulhern,Sumera Perveen, Germanna L Righetto,Patrick Riley, Suman Shrestha,Eric A Sigel, Madhushika Silva, Michael D. Sintchak,Belinda L Slakman, Rhys D Taylor, James Thompson,Wen Torng, Carl Underkoffler,Moritz von Rechenberg,Ian Watson,Derek J Wilson,Esther Wolf, Manisha Yadav, Aliakbar K Yazdi,Junyi Zhang,Ying Zhang,Vijayaratnam Santhakumar,Aled M Edwards,Dalia Barsyte-Lovejoy,Matthieu Schapira,Peter J Brown,Levon Halabelian,Cheryl H Arrowsmith

biorxiv（2024）

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A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins

Suzanne Ackloo,Fengling Li,Magda Szewczyk,Almagul Seitova,Peter Loppnau,Hong Zeng,Jin Xu,Shabbir Ahmad, Yelena A. Arnautova, A. J. Baghaie,Serap Beldar,Albina Bolotokova,Paolo A. Centrella,Irene Chau,Matthew A. Clark,John W. Cuozzo, Saba Dehghani-Tafti,Jeremy S. Disch,Aiping Dong, Antoine Dumas,Jianwen A. Feng,Pegah Ghiabi,Elisa Gibson,Justin Gilmer,Brian Goldman,Stuart R. Green,Marie-Aude Guie,John P. Guilinger,Nathan Harms, Oleksandra Herasymenko,Scott Houliston,Ashley Hutchinson,Steven Kearnes,Anthony D. Keefe,Serah W. Kimani,Trevor Kramer, Maria Kutera, Haejin A. Kwak,Cristina Lento,Yanjun Li, Jenny Liu,Joachim Loup,Raquel A. C. Machado,Christopher J. Mulhern,Sumera Perveen, Germanna L. Righetto,Patrick Riley, Suman Shrestha,Eric A. Sigel, Madhushika Silva, Michael D. Sintchak,Belinda L. Slakman, Rhys D. Taylor, James Thompson,Wen Torng, Carl Underkoffler,Moritz von Rechenberg,Ryan T. Walsh,Ian Watson,Derek J. Wilson,Esther Wolf, Manisha Yadav, Aliakbar K. Yazdi, Junyi Zhang,Ying Zhang,Vijayaratnam Santhakumar,Aled M. Edwards,Dalia Barsyte-Lovejoy,Matthieu Schapira,Peter J. Brown,Levon Halabelian,Cheryl H. Arrowsmith

Journal of medicinal chemistryno. 2 (2024): 1092-1112

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