Research Interests: Membrane and synaptic properties of mammalian CNS neurons/glia; Physiological, pharmacological and pathological studies of seizure disorders, using electrophysiological recordings, imaging and molecular biological techniques in vitro and in vivo; cerebral extracellular potassium regulation; brainstem seizures; and the use of human cerebral organoids derived from embryonic stem cells and from humans with epilepsy to study epilepsy and mitochondrial related disorders.