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Dr. Gregersen’s ongoing studies in the laboratory include international collaborative efforts to achieve a comprehensive description of the genetics of autoimmune diseases, with a particular focus on rheumatoid arthritis and systemic lupus erythematosus. At least 46 genetic regions have been identified for rheumatoid arthritis, but it is likely that many more remain to be discovered.
In addition, Dr. Gregersen is pursuing functional studies of a number of newly defined risk genes for autoimmunity, particularly genes that regulate the thresholds for activation of the immune system. Several of these genes for autoimmunity are potential targets of new drugs that may be able to modify activation thresholds, in order to either enhance or reduce aspects of the immune response. These studies include work on the following genes:
In addition, Dr. Gregersen is pursuing functional studies of a number of newly defined risk genes for autoimmunity, particularly genes that regulate the thresholds for activation of the immune system. Several of these genes for autoimmunity are potential targets of new drugs that may be able to modify activation thresholds, in order to either enhance or reduce aspects of the immune response. These studies include work on the following genes:
研究兴趣
论文共 519 篇作者统计合作学者相似作者
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Julia Delenko,Xiangying Xue,Prodyot K Chatterjee, Nathaniel Hyman,Andrew J Shih,Robert P Adelson,Polona Safaric Tepes,Peter K Gregersen, Christine N Metz
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Daniela Matuozzo,Estelle Talouarn,Astrid Marchal,Peng Zhang,Jeremy Manry,Yoann Seeleuthner, Yu Zhang,Alexandre Bolze, Matthieu Chaldebas,Baptiste Milisavljevic,Adrian Gervais,Paul Bastard,
Genome medicineno. 1 (2023): 22-22
Tomas Kirchhoff,Zhang-qun Chen,Bert Gold,Prodipto Pal,Mia M. Gaudet, Kristi Kosarin,Douglas A. Levine,Peter Gregersen, Sara Spencer, Megan Harlan,Mark Robson,Robert J. Klein,
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Tomas Kirchhoff,Zhang-qun Chen,Bert Gold,Prodipto Pal,Mia M. Gaudet, Kristi Kosarin,Douglas A. Levine,Peter Gregersen, Sara Spencer, Megan Harlan,Mark Robson,Robert J. Klein,
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medRxiv (Cold Spring Harbor Laboratory) (2023)
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Nature Geneticsno. 7 (2023): 1091-1105
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Anelia Horvath, Christoforos Giatzakis, Audrey Robinson-White,Sosipatros Boikos, Elizabeth Levine,Kurt Griffin,Erica Stein, Virginia Kamvissi,Payal Soni,Ioannis Bossis, Wouter de Herder,J. Aidan Carney,
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Journal of neurotrauma (2023)
Arthritis & Rheumatologyno. 4 (2023): 507-516
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