Research interests
Primary Immunodeficiency Diseases (PID):
molecular and cellular basis (specific antibody deficiency, CVID, ALPS, APECED syndrome, HLH)
genotype – phenotype correlations
development of novel treatments for PID and its complications

Atopic Diseases – particularly atopic dermatitis:
genetic and environmental factors
role of Staphylococcus aureus in triggering skin inflammation
use of immunosuppressants in children with severe atopic dermatitis
psychological impact on the family

Social responsibility
PID UK, Medical Advisory Panel
Anaphlylaxis Campaign, Healthcare Professional member
North West Paediatric Allergy Network, Chair
Royal College of Paediatrics and Child Health, Council Representative for North West
Royal College of Paediatrics and Child Health, Academic Advisor
American Academy of Allergy, Asthma and Immunology, Allergy Skin Diseases Group, Chair