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Research interest
We use structural biology to study the intrinsic pathway to cell death, controlled by the Bcl-2 family of proteins. We are seeking to better understand the molecular events that lead to the pro-apoptotic Bcl-2 family proteins Bax and Bak becoming active. We are exploiting this information to discover new drugs that interfere with the apoptotic pathway.
We use structural biology to study the intrinsic pathway to cell death, controlled by the Bcl-2 family of proteins. We are seeking to better understand the molecular events that lead to the pro-apoptotic Bcl-2 family proteins Bax and Bak becoming active. We are exploiting this information to discover new drugs that interfere with the apoptotic pathway.
研究兴趣
论文共 257 篇作者统计合作学者相似作者
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Christel Hendrieckx,Hanafi M. Husin,Sienna Russell-Green,Jennifer A. Halliday, Benjamin Lam,Steven Trawley,Sybil A. Mcauley,Leon A. Bach,Morton G. Burt,Neale D. Cohen,Peter G. Colman, D. Jane Holmes-Walker,
Laura E. Donaldson,Spiros Fourlanos,Sara Vogrin,Richard J. MacIsaac,Peter G. Colman,Sybil A. McAuley
INTERNAL MEDICINE JOURNALno. 1 (2024): 121-128
FRONTIERS IN ENDOCRINOLOGY (2023): 1295865
Acta diabetologicano. 6 (2023): 797-803
Agalya Periasamy,Naomi Mitchell,Olga Zaytseva, Arjun S. Chahal,Jiamin Zhao,Peter M. Colman,Leonie M. Quinn,Jacqueline M. Gulbis
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