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Dr. Black is a surgeon scientist with clinical subspecialty interest in the treatment of urologic cancers, including especially bladder and prostate cancer. He maintains a grant-funded translational research program in urothelial carcinoma with a focus on genomic analysis of response to chemotherapy, mechanisms of resistance to chemotherapy, and novel targeted therapies for bladder cancer. One of his main laboratory projects relates to Notch signaling in bladder cancer. His group was the first to identify Notch2 as an oncogene in bladder cancer, and they are now working to elucidate differential regulation of these oncogenic properties of Notch2 compared to the tumor suppressive properties of Notch1, with the objective of modulate both pathways independently for therapeutic purposes.
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论文共 20 篇作者统计合作学者相似作者
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Girish Kulkarni,Kyle Richards,Peter C. Black,Ricardo Rendon,Joseph Chin,Neal Shore,Gautam Jayram, Eugene Kramolowsky, Daniel Saltzstein,Piyush Agarwal,Laurence Belkoff,Michael O'Donnell,
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Tetsutaro Hayashi,A. Goriki, H.Z. Oo,Roland Seiler,Tilman Todenhöfer,Wolfgang Jaeger,S. Awrey, M. Altamirano-Dimas,Ladan Fazli,A. Matsubara,Peter McL. Black
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