基本信息
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个人简介
Dr. Roche uses molecular and cellular approaches to study to cell biology of lymphocyte activation by antigen presenting cells. More specifically, his work attempts to understand how dendritic cells, and other antigen presenting cells, generate and present peptide fragments of internalized foreign antigens to CD4 T cells. Antigen processing and presentation of MHC class II-peptide complexes to specific T cells is important for T cell development/selection as well as the ability of animals to mount immune responses to destroy foreign pathogens in the body.
Areas of Expertise
1) antigen presentation, 2) dendritic cell, 3) CD4 T cell, 4) ubiquitination, 5) endocytosis
研究兴趣
论文共 201 篇作者统计合作学者相似作者
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Journal of immunology (Baltimore, Md. : 1950)no. 12 (2023): 1814-1822
JOURNAL OF IMMUNOLOGYno. 1 (2022): 61.05-61.05
Molecular Immunology (2022): 33-33
biorxiv(2021)
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