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The cell wall is the key interface between bacteria and their environment. For a human pathogen like Mycobacterium tuberculosis that environment can be radically different during different stages of infection. The cell wall is comprised of a range of different molecules including a diverse group of complex glycopolymers. As with so many facets of biology, these structures are not static and their shape and composition can determine the outcome of interactions between the bacterium and its host or environment (summarised below). Work in Patrick’s laboratory focuses on how mycobacteria alter their cell wall in response to different environments, and how they turn cell wall structures over to support their growth and division.
All of this work incorporates a broad range of tools, drawn from microbiology, biochemistry, structural biology and analytical chemistry.
All of this work incorporates a broad range of tools, drawn from microbiology, biochemistry, structural biology and analytical chemistry.
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论文共 41 篇作者统计合作学者相似作者
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Karla Helena-Bueno, Mariia Yu. Rybak, Chinenye L. Ekemezie,Rudi Sullivan,Charlotte R. Brown, Charlotte Dingwall,Arnaud Baslé,Claudia Schneider,James P. R. Connolly,James N. Blaza, Bálint Csörgő,Patrick J. Moynihan,
Dema Alodaini,Victor Hernandez-Rocamora,Gabriela Boelter,Xuyu Ma, Micheal B Alao, Hannah M Doherty,Jack A Bryant,Patrick Moynihan,Danesh Moradigaravand,Monika Glinkowska,Waldemar Vollmer,Manuel Banzhaf
Omar Al-Jourani, Samuel T. Benedict,Jennifer Ross, Abigail J. Layton,Phillip van der Peet,Victoria M. Marando,Nicholas P. Bailey,Tiaan Heunis,Joseph Manion,Francesca Mensitieri, Aaron Franklin,Javier Abellon-Ruiz,
Omar Al-Jourani, Samuel Benedict,Jennifer Ross, Abigail Layton, Phillip van der Peet,Victoria M. Marando, Nicholas P. Bailey,Tiaan Heunis, Joseph Manion,Francesca Mensitieri, Aaron Franklin, Javier Abellon-Ruiz,
biorxiv(2022)
Sherry J Cheriyamkunnel,Saloni Rose,Pedro F Jacob, Lauren A Blackburn, Shaleen Glasgow, Jacob Moorse, Mike Winstanley,Patrick J Moynihan,Scott Waddell,Carolina Rezaval
Molecular microbiologyno. 1 (2021): 329-342
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