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Dr. Patricia Ferrieri's laboratory is focused on the pathogenesis of infections with group B streptococci (GBS) and host immunity to streptococcal antigens. These investigations have included the epidemiology of maternal and neonatal colonization and infection with GBS, animal models of neonatal sepsis and meningitis, isolation and biochemical and immunological characterization of key antigens of group B streptococci, and human and animal immune responses to these antigens, including the role of monoclonal and polyclonal antibodies in protection against infection. Her laboratory has cloned the gene for a key surface localized protein (glutamine synthetase) of GBS into E. coli, and has used polymerase chain reaction (PCR) technology and nucleotide sequencing and amino acid sequencing of this GBS protein to enhance the research.
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AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2023): S116-S117
American Journal of Ophthalmology Case Reports (2023): 101813-101813
Journal of Microbiology and Infectious Diseasespp.130-135, (2022)
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Current Microbiologyno. 8 (2021): 2956-2960
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Stefani N. Thomas,Ghaith Altawallbeh, Christopher Zaun,Kathryn Pape,Jennifer M. Peters,Philip J. Titcombe,Thamotharampillai Dileepan, Michael J. Rapp,Tyler D. Bold,Timothy W. Schacker,Sophie Arbefeville,Patricia Ferrieri,
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