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Prof Patric Turowski
Professor of Vascular Signalling
Institute of Ophthalmology
Faculty of Brain Sciences
Research summary
Vascular endothelial cells line blood vessels and play a major role in defining their phenotypic characteristics. Endothelial cells contribute to the servicing of tissues, e.g. by controlling entry of nutrients or immune cells. At the same time they act as custodians of tissue integrity and autonomy. Therefore, not surprisingly, co-ordinated signalling in endothelial cells is critical for tissue health. We primarily study signalling by reversible phosphorylation, mediated by complex networks of protein kinases and phosphatases, in three key areas of endothelial biology.
Professor of Vascular Signalling
Institute of Ophthalmology
Faculty of Brain Sciences
Research summary
Vascular endothelial cells line blood vessels and play a major role in defining their phenotypic characteristics. Endothelial cells contribute to the servicing of tissues, e.g. by controlling entry of nutrients or immune cells. At the same time they act as custodians of tissue integrity and autonomy. Therefore, not surprisingly, co-ordinated signalling in endothelial cells is critical for tissue health. We primarily study signalling by reversible phosphorylation, mediated by complex networks of protein kinases and phosphatases, in three key areas of endothelial biology.
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Silvia Dragoni, James T Brash,Alessandro Fantin, Charles Burridge,Laura Denti,Patric Turowski,Christiana Ruhrberg
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Soon-Gook Hong,Julianne W Ashby,John P Kennelly, Meigan Wu, Eesha Chattopadhyay, Rob Foreman,Peter Tontonoz,Patric Turowski, Marcus Gallagher-Jones,Julia J Mack
bioRxiv : the preprint server for biology (2023)
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Sarega Gurudas,Karen Frudd,Jayapal Jeya Maheshwari,Yeddula Rebecca Revathy,Sobha Sivaprasad, Shruthi Mahalakshmi Ramanathan,Vignesh Pooleeswaran,A Toby Prevost,Eleni Karatsai, Sandra Halim,Shruti Chandra,Paul Nderitu,
Journal of cell scienceno. 7 (2021): 1-34
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