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Research in my laboratory is dedicated to understanding the basis of infectious disease at molecular and cellular levels. We focus on mechanisms by which virulence factors produced by pathogenic microbes interact with host cell targets and thereby modulate host cell behavior during infection. We study these interactions in structural detail (i.e., at the level of atomic resolution through X-ray crystallography) in order to carry out precise biochemical, genetic, and cell biological experiments aimed at elucidating the mechanism of action of bacterial virulence factors in their cellular and organismal contexts.
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论文共 49 篇作者统计合作学者相似作者
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JOURNAL OF BIOLOGICAL CHEMISTRYno. 8 (2023): 104980-104980
bioRxiv : the preprint server for biology (2023)
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Jademilson C. Santos,Sumit Handa,Luis G. V. Fernandes,Lucas Bleicher,Cesar A. Gandin, Mario de Oliveira-Neto,Partho Ghosh,Ana Lucia T. O. Nascimento
Jori O Mills,Partho Ghosh
Cosmo Z. Buffalo, Adrian J. Bahn-Suh, Sophia P. Hirakis,Tapan Biswas,Rommie E. Amaro,Victor Nizet,Partho Ghosh
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