Pankaj K. Singh

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职业迁徙

个人简介

Clinical/Research Interests:
Cancer Metabolism and metabolic alterations in the regulation of chemotherapy and radiotherapy resistance in pancreatic cancer
Metabolic regulation of cancer cachexia
Nutritional interventions to prevent/revert wasting in cancer patients,
Tumor-stromal metabolic interactions
Metabolic regulation of stromal and immune microenvironment in pancreatic cancer
Metabolic regulation of stemness and cancer metastasis

研究兴趣

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Abstract 2334 Glycogen, a potential therapeutic target for Ewing Sarcoma

Yueying Liu,Lyndsay Young,Pankaj Singh,Harrison Clarke, Tara Hawkinson, Meagan McCall,Ramon Sun,Matthew Gentry

Journal of Biological Chemistryno. 3 (2024)

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Amphotericin B loaded nanoemulsion: Optimization, characterization and in-vitro activity against L. donovani promastigotes

Vikram Mohanlal Prajapat,Mayur Aalhate,Anitha Sriram,Srushti Mahajan,Indrani Maji,Ujala Gupta,Diksha Kumari,Kuljit Singh, Nitin Pal Kalia,Kamal Dua,Sachin Kumar Singh,Pankaj Kumar Singh

PARASITOLOGY INTERNATIONAL（2024）

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Emerging In Vitro and In Vivo Models: Hope for the Better Understanding of Cancer Progression and Treatment

Rachana Yadav,Srushti Mahajan,Hoshiyar Singh,Neelesh Kumar Mehra,Jitender Madan,Nandkumar Doijad,Pankaj Kumar Singh,Santosh Kumar Guru

Advanced biologypp.e2300487-e2300487, (2024)

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Implication of colloidal therapeutics in the treatment of vitiligo: Portray of signaling cascade, current drug-targets and preclinical and clinical evidences

Priti Paul,Harithasree Veerabomma,Ujala Gupta, Divya Atram,Pankaj Kumar Singh,Neelesh Kumar Mehra,Chandraiah Godugu,Ashish Baldi,Jitender Madan

Journal of Drug Delivery Science and Technologypp.105666, (2024)

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Design, development and characterization of the Apremilast and Indomethacin coamorphous system

Ekta Pardhi,Devendra Singh Tomar, Rahul Khemchandani,Gananadhamu Samanthula,Pankaj Kumar Singh,Neelesh Kumar Mehra

JOURNAL OF MOLECULAR STRUCTURE (2024): 137045-137045

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Metabolomic Investigations into Hypoxia-Mediated Metabolic Reprogramming of Pancreatic Cancer Cells

Vira Chumak, Girish H Rajacharya,Pankaj K Singh

Methods in molecular biology (Clifton, N.J.) (2024): 191-200

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Vitamin B6 Competition in the Tumor Microenvironment Hampers Antitumor Functions of NK Cells

Chunbo He,Dezhen Wang,Surendra K Shukla,Tuo Hu,Ravi Thakur,Xiao Fu,Ryan J King,Sai Sundeep Kollala,Kuldeep S Attri,Divya Murthy,Nina V Chaika,Yuki Fujii,

Cancer discovery（2024）

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Author Response: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

Nicholas J. Mullen,Surendra K. Shukla,Ravi Thakur,Sai Sundeep Kollala,Dezhen Wang,Nina Chaika,Juan F. Santana, William R. Miklavcic, Drew A. LaBreck,Jayapal Reddy Mallareddy,David H. Price,Amarnath Natarajan,

crossref（2024）

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K17-induced pyrimidine biosynthesis drives chemoresistance in PDAC

Yinghuan Lyu,Kenneth Shroyer,Chun-Hao Pan,Robert Tseng,Md Afjalus Siraj, Girish Halemirle Rajacharya, Bo Chen, Katie L. Donnelly,Michael Horowitz, Carlos Mauricio Mejia Arbelaez, Sumedha Chowdhury,Lyanne Oblein,

CANCER RESEARCHno. 2 (2024)

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Cancer-associated fibroblast-derived acetate promotes pancreatic cancer development by altering polyamine metabolism via the ACSS2–SP1–SAT1 axis

Divya Murthy,Kuldeep S. Attri,Surendra K. Shukla,Ravi Thakur,Nina V. Chaika,Chunbo He,Dezhen Wang,Kanupriya Jha,Aneesha Dasgupta,Ryan J. King,Scott E. Mulder,Joshua Souchek,

Nature Cell Biologyno. 4 (2024): 1-15

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