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职业迁徙
个人简介
Co-developer of a new approach to target alloreactive T cells and biomarker studies in a clinical PoC trial in kidney transplant patients (patent submitted); Co-developer and PI of the development of anti-CD4 mAb induced allo-tolerance in kidney; Co-inventor of novel tools for detecting antigen-specific T cells (e.g. protein-spanning peptide pool for stimulation- European patent approval 2009, outlicenced), Co-developer and PI of a novel approach for generating virus-specific T cells and first-in-man clinical PoC trial in solid organ transplant patients with severe CMV disease, Co-developer and PI of a new approach to target alloreactive T cells and clinical PoC trial in kidney transplant patients (patent submitted), Co-developer of diagnostic tests that has been commercialized (e.g. sIL-2R Immulite -Siemens, Quantibrite HLA-DR – Becton Dickinson, urinary IP-10 bedside test – Milenia Biotech), PI and co-developer of the concept of the “immunoparalysis” in ICU and transplant patients and resulting first-in-man PoC trials on immunostimulation by IFN- or GM-CSF in septic patients with “immunoparalysis”; PI and co-developer of a first-in-man PoC trial on selective immunoadsorption in severe sepsis, Co-developer of new transplant models which are close related to human being regarding the frequencies of allo-reactive memory T cells
研究兴趣
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Transplantationno. 1 (2024): 242-251
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Acta Materialia (2023): 118567-118220
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biorxiv(2023)
Journal of Nephrologyno. 4 (2022): 1071-1073
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