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个人简介
Pedro P. Lopez-Casas joined CNIO on July 2019 as Senior Scientist. I'm involved in the development of projects related to Prostate Cancer carcinogenesis and novel therapeutic approaches. Taking advantage of cutting-edge technology related to Precision Medicine (Next Generation Sequencing).
Ph.D. in 2000 under the supervision of Professor Dr. Lucas Sánchez at the Department of Cell and Developmental Biology in the Biological Research Center (CIB, CSIC), focused on the genetics and molecular biology of reproduction in invertebrates (Drosophila as model organism).
Postdoctoral training from 2000 to 2006 at the Molecular Biology of Gametogenesis Lab (Spanish National Research Council, CSIC), led by Professor Dr. Jesus del Mazo (Mentor). I was focusing on the regulation of gene expression in mammalians (Mouse as model organism).
Director of the R&D Laboratory at the "HM-Hospitales" from 2006 to 2009. I turned my research focus on Translational Oncology, giving support to the research projects within the “Clara Campal” Comprehensive Cancer Center. The achieved objectives were:
1) Founding a Mouse-based Preclinical Program (Patient-Derived Xenograft, PDX).
2) Founding a Human Tumor Biobank.
3) Involvement in developing an Early Clinical Trials Unit (Phase I).
Staff Scientist at the Spanish National Cancer Research Centre (CNIO) from 2009. My role was as Managing and Scientific Organizer of the Gastrointestinal Cancer Clinical Research Unit. The research focus of the Unit was the development of new therapeutic strategies in pancreatic cancer. My activities:
-Continuing a Mouse-based Preclinical Program.
-Executing and reporting National and International Competitive Research Projects.
-Collaboration with many Pharma and Biotech Companies from the US and Europe.
-Scientific guiding for all the personnel in training.
-Teaching in Masters and Animal Science Courses.
Awarded with the following accreditations by the ANECA institution in Spain: "Profesor de Universidad Privada", "Profesor Ayudante Doctor" y "Profesor Contratado Doctor".
Translational Research Director at Bioncotech Therapeutics (now Highlight Therapeutics), a CNIO spin-off, from 2018. I participated in the development of the lead drug candidate BO-112 (a best-in-class RNA-based therapy), which has been demonstrated to initiate a powerful immune response, turning ‘cold’ tumors ‘hot’ and now being tested in Phase II trials.
Currently, I'm back again to my former position at CNIO, as Staff Scientist, within the Prostate Cancer Clinical Research Unit.
研究兴趣
论文共 84 篇作者统计合作学者相似作者
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David Olmos,David Lorente,Daniel Alameda,Carlo Cattrini,Nuria Romero-Laorden,Rebeca Lozano,Pedro P. Lopez-Casas, Camille Capone, Anne Marie Vanden Broecke, Marco Trevisan, Suzy Van Sanden, Alexandra Jurgens,
JOURNAL OF CLINICAL ONCOLOGYno. 16 (2023): 5003-5003
TRANSLATIONAL RESEARCH (2023): 68-79
Elena Castro,Daniela Correia Salles,Rebeca Lozano,Heather Thorne,Isabel Aragon, Fernando Lopez Campos,Jose Rubio, Ana Gutierrez Pecharroman, Daniel Prieto,Isabel García,Maria I Pacheco,Casilda Llacer Perez,
Nuria Romero-Laorden,Rebeca Lozano,Casilda Llacer Perez, Jose Maria M. Piulats Rodriguez,Javier Puente,David Lorente,Ana Medina,Carlo Cattrini, Francesca Vitrone,Elena Almagro,Pablo Borrega,Nuria Lainez,
Myriam Fabre,Cristina Ferrer, Saioa Dominguez-Hormaetxe,Bruno Bockorny, Laura Murias,Oliver Seifert,Stephan A Eisler,Roland E Kontermann,Klaus Pfizenmaier,So Young Lee,Maria dM Vivanco,Pedro P Lopez-Casas,
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