Pablo Giraudi

Dr. Pablo Giraudi, PhD: He is a biotechnologist with education in liver diseases. During the last five years, he was involved in using in silico approaches for omics datasets integration and further use in biological networks to individuate protein biomarkers in non-alcoholic fatty liver (NAFLD) and other chronic liver diseases. He is involved in the design of studies to understand at the molecular level how the fibrogenic process develops in chronic liver diseases. In this project, he will work in experimental planning of the spatial transcriptomic project (ST), in ST data analysis and result interpretation, and validation at gene and protein level, using, among other methods, protein immunostaining of tissue sections and co-immunoprecipitation analysis in homogenate samples. MAJOR FIELDS OF RESEARCH EXPERIENCE  In silico omic strategies for biomarkers discovery in chronic liver diseases  Biomarkers validation  Molecular mechanisms in bilirubin neurotoxicity  Bilirubin chemical and biochemical aspects  Criobiology  Metabolic and viability studies in hepatocytes during cold preservation POSTDOCTORAL TRAINING: Participation in the course: Bioninformatics for discovery. Training on experimental design to the practice of bioinformatics, publically available data and bioinformatics resources., duration 100 h. European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, UK. 16-17 th March 2017. https://www.ebi.ac.uk/training/bioinformatics-for-discovery/bioinformatics-discovery Networks and Pathways. Practical course on how to explore and use protein interaction bioinformatic resources. European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, UK. 2-6 November 2015. https://www.ebi.ac.uk/training/events/2015/networks-and-pathways-0 Theoretical and practical course of high-performance liquid chomatography coupled to mass spectrometry, held by Aula Científica S. L. and performed in Alcalá de Henarez (Madrid – Spain), February 23-26 (2011), duration: 28 h. http://www.aulacientifica.com/ Principles and Applications of Time-Resolved Fluorescence Spectroscopy held by Picoquant, Germany, November 01 – 04 (2011). http://www.picoquant.com/events/workshops-and-courses EDUCATION AND TRAINING • 2006 – 2009: PhD in Bio-molecular Sciences given by the Università degli Studi di Trieste Thesis title: Mechanisms involved in the UCB neurotoxicity on cellular models. • 1996 – 2004: Degree in Biotechnology given by the Universidad Nacional de Rosario. (Facultad de Biochímica y Ciencias Farmacéuticas - Argentina)