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The De Camilli lab is interested in the cell biology of neuronal synapses. His studies on synaptic vesicle dynamics have contributed to the general fields of exocytosis and endocytosis. His research has provided insight into mechanisms of membrane fission and has revealed ways through which membrane-associated proteins can generate, sense and stabilize lipid bilayer curvature. His discovery and characterization of the role of phosphoinositide metabolism in the control of endocytosis have broad implications in the fields of phospholipid signaling and of membrane traffic. Building on this work, he has recently become interested in the role of membrane contact sites in the control of the homeostasis of bilayer lipids. His studies of synapses have also contributed to the elucidation of pathogenetic mechanisms of human diseases, with recent emphasis on Parkinson's disease.
研究兴趣
论文共 566 篇作者统计合作学者相似作者
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Nature Cell Biologyno. 2 (2024): 173-173
bioRxiv : the preprint server for biology (2024)
Journal of Cell Biologyno. 7 (2023)
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Annual review of cell and developmental biologyno. 1 (2023): 409-434
MOLECULAR BIOLOGY OF THE CELLno. 2 (2023): 233-233
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bioRxiv (Cold Spring Harbor Laboratory) (2023): 25152564231215133-25152564231215133
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