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Omer H. Yilmaz explores the impact of dietary interventions on stem cells, the immune system, and cancer within the intestine.
The adult intestine is maintained by stem cells that require a cellular neighborhood, or niche, consisting in part of Paneth cells. Our laboratory will investigate the molecular mechanisms of how intestinal stem cells and their Paneth cell niche respond to diverse diets to coordinate intestinal regeneration with organismal physiology and its impact on the formation and growth of intestinal cancers. By better understanding how intestinal stem cells adapt to diverse diets, we hope to identify and develop new strategies that prevent and reduce the growth of cancers involving the intestinal tract that includes the small intestine, colon, and rectum.
The adult intestine is maintained by stem cells that require a cellular neighborhood, or niche, consisting in part of Paneth cells. Our laboratory will investigate the molecular mechanisms of how intestinal stem cells and their Paneth cell niche respond to diverse diets to coordinate intestinal regeneration with organismal physiology and its impact on the formation and growth of intestinal cancers. By better understanding how intestinal stem cells adapt to diverse diets, we hope to identify and develop new strategies that prevent and reduce the growth of cancers involving the intestinal tract that includes the small intestine, colon, and rectum.
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论文共 176 篇作者统计合作学者相似作者
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Nature Cell Biologyno. 1 (2024): 41-42
AMERICAN JOURNAL OF SURGICAL PATHOLOGYno. 1 (2024): 70-79
Natureno. 8004 (2024): 636-645
bioRxiv : the preprint server for biology (2023)
CANCER RESEARCHno. 7 (2023)
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Martin S Taylor,Connie Wu,Peter C Fridy,Stephanie J Zhang,Yasmeen Senussi,Justina C Wolters, Tatiana Cajuso, Wen-Chih Cheng, John D Heaps, Bryant D Miller, Kei Mori,Limor Cohen,
biorxiv(2023)
Jonathan M. Downie, Connor M. Geraghty,Thaddeus S. Stappenbeck,Omer H. Yilmaz,David A. Drew,Andrew T. Chan
CANCER RESEARCHno. 7 (2023)
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Daniel R. Schmidt, Iva Monique T. Gramatikov,Allison Sheen,Christopher L. Williams,Martina Hurwitz,Laura E. Dodge, Edward Holupka, W. S. Kiger III, Milton R. Cornwall-Brady,Wei Huang,Howard H. Mak, Kathleen S Cormier,
Communications Medicineno. 1 (2023): 1-20
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Journal of clinical pathology (2023)
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