He has conducted extensive research in PAH and he is the scientific leader of the French PH Registry. His investigational activities include clinical studies on factors associated with PAH, identification of prognostic factors, studies on risk stratification and treatment goals in PAH, and the development of new strategies for the treatment of PAH. He co-chaired the working group on “Trials Design & New Therapies for PAH” at the 6th World PH Symposium in 2018, and was a task force member and section editor of the 2022 ESC-ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. He has authored more than 410 peer-reviewed articles on PH and related topics in the major scientific journals.