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个人简介
Dr. Niсkolai A. Tchurikov, Doctor of Sciences (D. Sci.- molecular biology), now is a Head of Department of Epigenetic Mechanisms of Gene Expression Regulation, Engelhardt Institute of Molecular Biology, Moscow, Russia. He got his Medicine Doctor's degree (M.D.) at Stavropol State Medical Institute in 1972. In 1977 he got his Molecular Biology Ph.D. at Engelhardt Institute of Molecular Biology, Moscow, USSR. Winner of the State Award of USSR for the discovery on molecular level of mobile elements in eukaryotes, 1983. 1977 – Ph.D.- “Discovery and properties of mobile element Dm225 in Drosophila genome”. 1989 – D.Sci. – “Molecular organization of the cut locus in Drosophila melanogaster”. In 1977-1980 discovered at molecular level mobile genetic elements in Drosophila and clusters of different mobile elements. In 1981-1989 cloned entire complex cut locus from Drosophila and detected multiple transpositions events in the locus and several new mobile elements. In 1988-2000 detected the physical capacity of DNA and RNA molecules to form parallel duplexes. In 1998 sequenced completely a novel LTR-element, burdock. In 1988-2015 detected large chromosomal domains corresponding to the units of coordinated genes expression, trans-RNAi. Current interests – epigenetic mechanisms in regulation of genes expression, regulation of siRNA and piRNA pathways of silencing, study of higher-order chromosomal structures by 4C, development of RNAi approach for AIDS/HIV treatment.
研究兴趣
论文共 78 篇作者统计合作学者相似作者
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N. A. Tchurikov, A. A. Vartanian, E. S. Klushevskaya, I. R. Alembekov, A. N. Kretova, V. R. Chechetkin, G. I. Kravatskaya, V. S. Kosorukov, Y. V. Kravatsky
International journal of molecular sciencesno. 12 (2023): 9842-9842
N. A. Tchurikov, I. R. Alembekov, E. S. Klushevskaya, P. B. Meilakh, A. N. Kretova, O. D. Managarova, G. I. Kravatskaya, Yu. V. Kravatsky
Nickolai A. Tchurikov,Ildar R. Alembekov,Elena S. Klushevskaya,Antonina N. Kretova, Ann M. Keremet, Anastasia E. Sidorova, Polina B. Meilakh,Vladimir R. Chechetkin,Galina Kravatskaya,Yuri Kravatsky
FEBS OPEN BIO (2021): 105-105
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