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论文共 11 篇作者统计合作学者相似作者

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USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by downregulating fibroblast VEGF

Anamarija Jurisic, Pei-Ju Sung,Mark Wappett, Julien Daubriac,Ian T Lobb, Wei-Wei Kung, Nyree Crawford,Natalie Page, Eamon Cassidy, Stephanie Feutren-Burton,J S Shane Rountree, Matthew D Helm,

Clinical and translational medicineno. 4 (2024): e1648-e1648

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A novel first-in-class USP19 inhibitor for the treatment of cancer-induced muscle atrophy

Natalie Page, Vignesh Karthikaisamy, Darren O'Hara,Aaron N. Cranston, Colin R. O'Dowd,Xavier Jacq, Richard Wilkinson,Stephanie Burton, Hayley Gibson,Joana Costa,Daniel Longley,Matthew Helm,

CANCER RESEARCHno. 8 (2023)

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Abstract LB022: A novel first-in-class USP19 inhibitor for the treatment of cancer-induced muscle atrophy

Natalie Page, Vignesh Karthikaisamy, Darren O'Hara,Aaron Cranston, Colin O’Dowd,Xavier Jacq, R. Wilkinson,Stephanie Gail Burton, Hayley Gibson,Joana Costa, Daniel B. Longley,Matthew Helm,

Cancer Researchno. 8_Supplement (2023): LB022-LB022

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Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development

Natalie Page,Mark Wappett,Colin R. O’Dowd, Martin O’Rourke,Gerald Gavory,Lixin Zhang,J. S. Shane Rountree,Linda Jordan,Oliver Barker, Hayley Gibson,Caroline Boyd,Stephanie Feutren-Burton,

SCIENTIFIC REPORTS（2022）

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Deubiquitinases and their inhibitors: challenges and recent advances

Peter R. Hewitt,Oliver Barker,Matthew Helm,Xavier Jacq, Colin O’Dowd,Natalie Page,J. S. Shane Rountree,Timothy Harrison

Medicinal chemistry reviewspp.363-387, (2022)

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Targeting the ubiquitin-proteasome system by small molecule inhibition of the DUBome

Tim Harrison,Xavier Jacq,Colin O'Dowd,Gerald Gavory,Oliver Barker,Christina Bell,Frank Burkamp,Stephanie Burton, Eamon Cassidy,Matthew Helm,Peter Hewitt,Natalie Page,

CANCER RESEARCH（2019）

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Discovery and characterization of highly potent and selective USP7 inhibitors and benchmarking against clinical MDM2 antagonists

Gerald Gavory,Colin O'Dowd, Elias Arkoudis,Oliver Barker, Eamon Cassidy,Anthony Dossang,Jakub Flasz, Matt Helm,Caroline Hughes,Keeva McClelland, Hugues Miel, Ewa Odrzywol,

Cancer Research（2018）

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Accessing the cancer DUBome with UbiPlex: A bespoke drug discovery platform for deubiquitinase enzymes

Gerald Gavory,Colin O'Dowd,Oliver Barker,Christina Bell,Frank Burkamp,Stephanie Burton, Eamon Cassidy,Joana Costa,Anthony Dossang, Matt Helm,Ashling Henderson,Peter Hewitt,

Cancer Research（2018）

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Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors

Colin R O'Dowd,Matthew D Helm,J S Shane Rountree,Jakub T Flasz, Elias Arkoudis, Hugues Miel, Peter R Hewitt,Linda Jordan,Oliver Barker,Caroline Hughes, Ewelina Rozycka, Eamon Cassidy,

ACS medicinal chemistry letters（2018）

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Discovery and characterization of highly potent and selective allosteric USP7 inhibitors

Gerald Gavory, Colin R O'Dowd,Matthew D Helm, Jakub Flasz, Elias Arkoudis,Anthony Dossang,Caroline Hughes, Eamon Cassidy,Keeva McClelland, Ewa Odrzywol,Natalie Page,Oliver Barker,

NATURE CHEMICAL BIOLOGY（2017）

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