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职业迁徙
个人简介
My research focus lies in genetically dissecting those aspects of Aspergillus spp. that render them potent pathogens and superb natural product machines. We are interested in elucidating the mechanism of fungal sporulation and host/pathogen interactions; processes intimately linked to secondary metabolite (e.g. mycotoxin) production. My tactic has been to use the genetic model Aspergillus nidulans to elucidate important biological processes in this genus and then carry this information to the plant pathogens A. flavus and A. parasiticus and the human pathogen A. fumigatus. The former two pathogens contaminate seed crops worldwide with aflatoxin, the most potent naturally occurring carcinogen known. The latter pathogen is now tied with Candida as the most serious human mycopathogen in developed countries where it can cause invasive aspergillosis, a disease with a mortality rate ranging from 50 to 90%.
研究兴趣
论文共 434 篇作者统计合作学者相似作者
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Morgan A Giese,David A Bennin,Taylor J Schoen, Ashley N Peterson, Jonathan H Schrope, Josh Brand,Ho Sun Jung,Nancy P Keller,David J Beebe,Huy Q Dinh,Igor I Slukvin,Anna Huttenlocher
Journal of leukocyte biology (2024)
Hye-Won Seo, Natalia S Wassano, Mira Syahfriena Amir Rawa,Grant R Nickles,André Damasio,Nancy P Keller
Journal of fungi (Basel, Switzerland)no. 4 (2024): 266
Hye-Won Seo, Natalia S. Wassano, Mira Syahfriena Amir Rawa,Grant R. Nickles,André Damasio,Nancy P. Keller
Journal of Fungino. 4 (2024): 266
Sung Chul Park,Breanne N Steffan,Fang Yun Lim,Raveena Gupta,Fatma Ayaloglu Butun, Hongyu Chen,Rosa Ye, Timothy Decker,Chengcang C Wu,Neil L Kelleher,Jin Woo Bok,Nancy P Keller
Kunlong Yang, Yue Luo,Tongzheng Sun, Han Qiu,Qingru Geng,Yongxin Li,Man Liu,Nancy P. Keller,Fengqin Song,Jun Tian
Journal of Hazardous Materialspp.134385, (2024)
Nature communicationsno. 1 (2023): 7351-16
PLoS Pathogensno. 5 (2023): e1011152
Frontiers in microbiology (2023): 1208961
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