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个人简介
Dr. Akizu's research focuses on cerebellar ataxias and motoneuron disorders, with the specific goals of uncovering the particularities of these neuronal types, understanding disease mechanisms, and exploring treatment options.
OUR RESEARCH INTEREST:
To better understand human brain complexity in health and disease, with the ultimate goal to uncover therapeutic targets for neurological disorders.
OUR RESEARCH APPROACH:
Our current focus is in the study of neurodevelopmental and degenerative disorders. We combine animal models and human stem cell derived cultures, and apply DNA/RNA sequencing, epigenomics, proteomics and imaging methods to gain insights into functional and molecular differences between resistant and vulnerable cells. Information that we gather from these studies will serve to better understand disease mechanisms and develop treatment strategies.
OUR RESEARCH INTEREST:
To better understand human brain complexity in health and disease, with the ultimate goal to uncover therapeutic targets for neurological disorders.
OUR RESEARCH APPROACH:
Our current focus is in the study of neurodevelopmental and degenerative disorders. We combine animal models and human stem cell derived cultures, and apply DNA/RNA sequencing, epigenomics, proteomics and imaging methods to gain insights into functional and molecular differences between resistant and vulnerable cells. Information that we gather from these studies will serve to better understand disease mechanisms and develop treatment strategies.
研究兴趣
论文共 33 篇作者统计合作学者相似作者
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Carolina Gracia-Diaz, Jonathan E. Perdomo,Munir E. Khan, Thomas Roule, Brianna L. Disanza, Gregory G. Cajka, Sunyimeng Lei,Alyssa L. Gagne,Jean Ann Maguire,Ophir Shalem,Elizabeth J. Bhoj,Rebecca C. Ahrens-Nicklas,
Cell Stem Cellno. 3 (2024): 288-289
Marco Flores-Mendez, Laura Ohl, Thomas Roule,Yijing Zhou,Jesus A Tintos-Hernández, Kelsey Walsh,Xilma R Ortiz-González,Naiara Akizu
bioRxiv : the preprint server for biology (2024)
Carolina Gracia-Diaz, Jonathan E Perdomo,Munir E Khan, Brianna Disanza,Gregory G Cajka,Sunyimeng Lei,Alyssa Gagne,Jean Ann Maguire, Thomas Roule,Ophir Shalem,Elizabeth J Bhoj,Rebecca C Ahrens-Nicklas,
bioRxiv : the preprint server for biology (2023)
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Science advancesno. 10 (2023): eade1463-eade1463
Nature Communicationsno. 1 (2023): 1-18
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Yijing Zhou, Vanessa B. Sanchez,Peining Xu,Marco Flores-Mendez, Brianna Ciesielski, Donna Yoo,Hiab Teshome,Mike Henne, Tim O'Brien,Clementina Mesaros,Naiara Akizu
biorxiv(2022)
medRxiv (Cold Spring Harbor Laboratory) (2022)
E. J. Bhoj,D. Li, M. H. Harr, H. Hakonarson, M. Martinez-Balbas,C. Smith-Hicks, A. Chassevent,S. Mohammed, P. Mark, A. Holtz, L. Rodan,P. Agrawal,
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