Dr. Saba is a well-recognized expert in immunotherapy for head and neck cancer and upper aero-digestive malignancies. His work is focused on translational research and the study and development of novel therapeutic agents and modalities in these diseases. He has been principal investigator in more than 50 clinical trials and chairs national as well as investigator initiated multi-institution studies focusing on novel approaches for treating head and neck and esophageal cancer. Dr Saba has been instrumental in establishing the head and neck cancer research working group at Winship Cancer Institute and is the contact principal investigator of the Lead Academic Participating Site (LAPS) grant of the NCI’s National Clinical Trials Network (NCTN).