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个人简介
Dr. Moshe Talpaz’s academic career is intertwined with the therapeutic developments in Chronic Myeloid Leukemia (CML). Over a period of 30 years Dr. Talpaz pioneered the development of Interferon therapy for CML and was one of three investigators (Charles Sawyers and Brian Druker) who conducted the first clinical studies with the now renowned targeted therapy for CML - Gleevec. He later pioneered the development of Sprycel as a new targeted therapy for CML which overcomes resistance to Gleevec. This work was published in the New England Journal of Medicine, the most prestigious medical journal, in 2006.
Dr. Talpaz has developed a large program dealing with CML at the University of Michigan which has garnered much recognition. As a result he was asked to lead the development of a novel and exciting new drug (a third generation BCR-ABL inhibitor) for resistant CML, Ponatinib (Iclusig). This work was published in the New England Journal of Medicine in November, 2012.
Dr. Talpaz has developed a large program dealing with CML at the University of Michigan which has garnered much recognition. As a result he was asked to lead the development of a novel and exciting new drug (a third generation BCR-ABL inhibitor) for resistant CML, Ponatinib (Iclusig). This work was published in the New England Journal of Medicine in November, 2012.
研究兴趣
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Samuel Benjamin Reynolds, Sho Matono,Malathi Kandarpa, Kristen Pettit,Mark Ribick,Moshe Talpaz, Qing Li
Cancer Researchno. 6_Supplement (2024): 3628-3628
Magnetic resonance in medicine (2024)
Haematologicano. 4 (2024)
Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Neil P Shah,Ravi Bhatia,Jessica K Altman, Maria Amaya,Kebede H Begna,Ellin Berman,Onyee Chan, Joan Clements,Robert H Collins,Peter T Curtin,Daniel J DeAngelo, Michael Drazer,
Journal of the National Comprehensive Cancer Network : JNCCNno. 1 (2024): 43-69
Srdan Verstovsek,Moshe Talpaz,Martha Wadleigh,Alessandro Isidori,Peter Te Boekhorst,Michael R Savona,Prithviraj Bose,Olga Pozdnyakova,Ruben Mesa, Tarec C El-Galaly, Jennifer O'Sullivan, Katia Gamel,
Haematologica (2024)
crossref(2024)
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