Dr. Wharam co-lead a groundbreaking study of treatment reduction in Hodgkin’s lymphoma, which led to refinements in therapy. He also developed the standard of care for rhabdomyosarcoma, a childhood cancer of the connective tissue that attaches muscles to bones, combining chemotherapy and radiation therapy, a treatment so effective it remains the standard today.

In the early 1990s, years before advanced radiosurgery equipment had been developed, Dr. Wharam innovated a way to deliver radiation very precisely to preserve vision for a toddler diagnosed with cancer in both eyes.