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Since I graduated from Medical School, my major activity as a physician has been linked to my professional goals. Both as a physician and an investigator, I have worked to improve the treatment of patients with chronic kidney failure. Consequently, I serve as the physician for patients with chronic kidney failure and in treating them, I have uncovered specific problems that develop in these patients. This has led to the development of methods of ameliorating the problems caused by kidney diseases, including insights into methods for slowing the progress of kidney failure. My experimental efforts have been closely linked to the goal of preventing complications of kidney disease and fortunately, we have made progress in not only determining how kidney damage changes the metabolism of protein in the body but also how the diet can be manipulated to ameliorate clinical problems of patients with chronic kidney failure. Specifically, we have identified how kidney failure changes the metabolism of muscle, resulting in loss of muscle mass and strength. We are working on two different strategies that have the potential of preventing the loss of muscle mass and this is has led to promising results that are being tested in patients with kidney failure.
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Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundationno. 6 (2023): S88-S92
CIRCULATION (2023)
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Journal of the American Society of Nephrology : JASNno. 1 (2023): 1-2
Staying Healthy with Kidney Diseasepp.51-72, (2022)
William E. Mitch, Stephen Z. Fadem
Staying Healthy with Kidney Diseasepp.83-86, (2022)
Circulation Researchno. 3 (2022): 207-221
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