Dr. Chung has been principal investigator or co-investigator in a number of important clinical trials studying atrial fibrillation, supraventricular and ventricular arrhythmias, cardioversion, pacemaker and defibrillator therapy, biventricular pacing for heart failure and catheter ablation approaches. Along with colleagues at Cleveland Clinic, she reported the first association of inflammation with persistence of atrial fibrillation. She has also been a Principal Investigator for AFFIRM (Atrial Fibrillation Follow-up Investigation of Rhythm Management), a multicenter randomized trial of rate-control versus rhythm-control strategies for atrial fibrillation. In this study, she has led analyses that demonstrate functional status benefits that help to justify and rationalize maintenance of sinus rhythm in patients with symptomatic atrial fibrillation. She is also investigating the genetics of arrhythmias, including atrial fibrillation. Dr. Chung has been an invited lecturer to numerous national conferences to present findings from her research.