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个人简介
Current Research and Scholarly Interests
The primary aim of my lab is to enable early detection and precision treatment of devastating brain diseases by developing translational molecular imaging agents for visualizing neuroimmune interactions underlying conditions such as Alzheimer’s disease, multiple sclerosis, and stroke.
We are researching how the brain and its resident immune cells interact with the peripheral immune system at very early, through to late stages of disease. Our approach involves the discovery, characterization, and validation of clinically relevant immune cell biomarkers, followed by the design of novel positron emission tomography (PET) radiotracers specifically targeting these biomarkers. After preclinical validation, we translate promising imaging probes to the clinic for precision targeting of immunomodulatory therapeutics and real-time monitoring of treatment response.
The primary aim of my lab is to enable early detection and precision treatment of devastating brain diseases by developing translational molecular imaging agents for visualizing neuroimmune interactions underlying conditions such as Alzheimer’s disease, multiple sclerosis, and stroke.
We are researching how the brain and its resident immune cells interact with the peripheral immune system at very early, through to late stages of disease. Our approach involves the discovery, characterization, and validation of clinically relevant immune cell biomarkers, followed by the design of novel positron emission tomography (PET) radiotracers specifically targeting these biomarkers. After preclinical validation, we translate promising imaging probes to the clinic for precision targeting of immunomodulatory therapeutics and real-time monitoring of treatment response.
研究兴趣
论文共 130 篇作者统计合作学者相似作者
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Journal of nuclear medicine : official publication, Society of Nuclear Medicine (2024)
Edward N. Wilson,Congcong Wang,Michelle S. Swarovski,Kristy A. Zera,Hannah E. Ennerfelt,Qian Wang,Aisling Chaney,Esha Gauba, Javier A. Ramos Benitez,Yann Le Guen,Paras S. Minhas, Maharshi Panchal,
Nature Neurosciencepp.1-13, (2024)
Katrin I Andreasson,Edward N Wilson,Congcong Wang, Matthew Xin,Maharshi Panchal,Joshua D Rabinowitz,Paras S Minhas,Michelle S Swarovski,Javier A Ramos Benitez, Aarooran S Durairaj,Aisling Chaney, Chinyere A Iweka,
biorxiv(2024)
Seminars in nuclear medicineno. 5 (2023): 687-693
International Journal of Qualitative Methods (2023)
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