基本信息
浏览量:8
职业迁徙
个人简介
Our research is centered on determination of the structure and/or reaction dynamics and reaction mechanism of a number of exotic species in the gas phase. These studies all utilize state-of-the-art ion beam technologies and methodologies, most of which were developed in our lab. The work is a blend of experiment and theory. We bring a chemical physics outlook to problems of chemical and biological interest.
At present, we are involved in two broad areas: nanoclusters/materials and conformations, energeitcs and hydration of macromolecular systems. In the nanocluster/materials area, we are looking at size-selected metal clusters, their binding energies to catalytically important ligands and the connection to the same chemistry on clean semiconducter surfaces. The surface work is done in collaboration with Profs. Buratto, McFarland, Metiu and Moscovitz. Other projects include development of conducting organic films for use as LED's and other electronic devices (in collaboration with the Buratto and Bazan groups) and the hydration/dissolution energetics and mechanism of small sea salt clusters.
We are interested in macromolecular systems of both industrial and biological importance. Industrial systems include primary and secondary structural/conformational mapping of both pure and copolymer systems. Of particular interest are polyhedral oligomeric silsesquioxanes (POSS), silicon/oxygen cages that greatly enhance polymer properties when attached.
Biopolymer work has focused on the importance of conformational analysis, salt bridge formation and hydration of both peptides and oligonucleotides. This work continues. New projects are aimed at misfolding/aggregation phenomena that underlie many diseases, including Alzheimer's and various transmissible spongiform encephalopathies (TSE). Both experimental and theoretical approaches are being pursued.
At present, we are involved in two broad areas: nanoclusters/materials and conformations, energeitcs and hydration of macromolecular systems. In the nanocluster/materials area, we are looking at size-selected metal clusters, their binding energies to catalytically important ligands and the connection to the same chemistry on clean semiconducter surfaces. The surface work is done in collaboration with Profs. Buratto, McFarland, Metiu and Moscovitz. Other projects include development of conducting organic films for use as LED's and other electronic devices (in collaboration with the Buratto and Bazan groups) and the hydration/dissolution energetics and mechanism of small sea salt clusters.
We are interested in macromolecular systems of both industrial and biological importance. Industrial systems include primary and secondary structural/conformational mapping of both pure and copolymer systems. Of particular interest are polyhedral oligomeric silsesquioxanes (POSS), silicon/oxygen cages that greatly enhance polymer properties when attached.
Biopolymer work has focused on the importance of conformational analysis, salt bridge formation and hydration of both peptides and oligonucleotides. This work continues. New projects are aimed at misfolding/aggregation phenomena that underlie many diseases, including Alzheimer's and various transmissible spongiform encephalopathies (TSE). Both experimental and theoretical approaches are being pursued.
研究兴趣
论文共 108 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Xikun Liu, Shuya Duan,Yingying Jin, Ethan Walker, Michelle Tsao, Joshua H. Jang, Ziying Chen,Ambuj K. Singh,Kristi Lazar Cantrell,Helgi I. Ingolfsson,Steven K. Buratto,Michael T. Bowers
ACS CHEMICAL NEUROSCIENCEno. 24 (2023): 4395-4408
Biophysical journalno. 22 (2023): 4370-4381
ACS chemical neuroscienceno. 15 (2023): 2717-2726
ACS Chemical Neuroscienceno. 9 (2019): 4112-4123
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn