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个人简介
My research involves X-ray crystallographic studies of macromolecular assemblies and enzymes involved in DNA metabolism, such as helicase/primase, dihydrofolate reductase (DHFR) and DNA polymerase beta (polB). Past projects include construction of a crystallographic movie of DHFR, depicting loop and subdomain conformational movements during one turnover of substrate. I have also written a web server for treating anisotropy in X-ray crystallographic data sets.
研究兴趣
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Kyle Meador,Roger Castells-Graells, Roman Aguirre,Michael R. Sawaya,Mark A. Arbing, Trent Sherman,Chethaka Senarathne,Todd O. Yeates
Structure (2024)
Bryan D. Ryder, Elizaveta Ustyantseva,David R. Boyer,Ayde Mendoza-Oliva, Mikołaj I. Kuska,Paweł M. Wydorski, Paulina Macierzyńska, Nabil Morgan,Michael R. Sawaya,Marc I. Diamond,Harm H. Kampinga,Lukasz A. Joachimiak
Structure (2024)
Justin E Miller, Matthew P Agdanowski, Joshua L Dolinsky,Michael R Sawaya,Duilio Cascio,Jose A Rodriguez,Todd O Yeates
Acta crystallographica. Section D, Structural biology (2024)
Binh An Nguyen,Virender Singh,Shumaila Afrin, Anna Yakubovska, Lanie Wang,Yasmin Ahmed, Rose Pedretti,Maria del Carmen Fernandez-Ramirez, Preeti Singh, Maja Pękała, Luis O. Cabrera Hernandez, Siddharth Kumar,
Nature Communicationsno. 1 (2024): 1-12
Romany Abskharon,Hope Pan,Michael R Sawaya,Paul M Seidler, Eileen J Olivares,Yu Chen,Kevin A Murray, Jeffrey Zhang,Carter Lantz, Megan Bentzel,David R Boyer,Duilio Cascio,
Proceedings of the National Academy of Sciences of the United States of Americano. 41 (2023): e2300258120-e2300258120
Nature Communicationsno. 1 (2023): 1-18
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