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职业迁徙
个人简介
My research interests involve mechanistic studies of serious adverse drug reactions with a specific focus on drug hypersensitivity. Our group is working on determining the relative contributions of metabolism and immune response in the development of drug hypersensitivity to a number of drugs including commonly used antibiotics, anti-epilepsy drugs and chemotherapeutic agents. More recently we are investigating how genetically determined variations in drug metabolism, immune response, drug transport and cellular repair determine risk for serious adverse events to chemotherapy for childhood cancer. Our laboratory also has a long-standing interest in steroid biology and the impact of stress on corticosteroid production. We are also involved in a series of clinical studies to define optimal therapy for children in acute and emergency care settings. More recent areas of focus in our laboratory are studies on point of care diagnostics for food and drug safety and in the development of wireless sensor systems for the evaluation of pharmacological responses.
研究兴趣
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PAEDIATRICS & CHILD HEALTHno. 1 (2024): 12-16
Sylvia Martinez-Cabriales, Jerome Coulombe, Michelle Aaron, Sadaf H. Hussain, Danny Linggonegoro,Irene Lara-Corrales, Hailey Barootes, Heather Brandling-Bennett, Isabela Covelli,Anna Yasmine Kirkorian,Nidhi Shah,Leslie Castelo-Soccio,
Naima Abouseta,Noha Gomaa,Ali Tassi,Abdelbaset A Elzagallaai,Michael J Rieder, S Jeffrey Dixon,Sharat C Pani
Caries research (2024)
Paediatrics & child healthno. 2 (2024): 104-121
The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAGno. 4 (2023): 343-347
Paediatrics & child healthno. 4 (2023): 205-251
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