Michael F. Beers
教授
Pulmonary
Allergy, and Critical Care Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania;PENN Lung Biology Institute, Perelman School of Medicine, University of Pennsylvania;Hospital of University of Pennsylvania;Philadelphia Veterans Affairs Medical Center;United Community Clinic Philadelphia PA
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基本信息
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职业迁徙
个人简介
Michael Beers has pursued an academic career centered in basic research of lung epithelial cell biology and surfactant protein metabolism.
Dr Beers serves as Group Leader for the following active projects:
Epithelial Dysfunction and Parenchymal Lung Disease. We are using novel mouse models of pulmonary fibrosis to characterize the mechanisms underlying the development of the cellular dysfunction driving the cascade of inflammatory and aberrant remodeling events leading to pulmonary fibrosis in vivo. Current projects focus on metabolic reprogramming, AT2-mesenchyme cross talk, roles for treg and monocyte/macrophase lineages, ER stress, and identification of new pulmonary fibrosis targets using 'omics' approaches.
Biosynthetic Pathways for SP-C: The cellular metabolism of surfactant protein C with emphasis on the intracellular trafficking of SP-C and the cellular quality control pathways of AT2 cells.
Innate Immunity and Inflammation- The role of pulmonary collectins (surfactant proteins A and D) in the modulation of inflammation and injury.
Dr Beers serves as Group Leader for the following active projects:
Epithelial Dysfunction and Parenchymal Lung Disease. We are using novel mouse models of pulmonary fibrosis to characterize the mechanisms underlying the development of the cellular dysfunction driving the cascade of inflammatory and aberrant remodeling events leading to pulmonary fibrosis in vivo. Current projects focus on metabolic reprogramming, AT2-mesenchyme cross talk, roles for treg and monocyte/macrophase lineages, ER stress, and identification of new pulmonary fibrosis targets using 'omics' approaches.
Biosynthetic Pathways for SP-C: The cellular metabolism of surfactant protein C with emphasis on the intracellular trafficking of SP-C and the cellular quality control pathways of AT2 cells.
Innate Immunity and Inflammation- The role of pulmonary collectins (surfactant proteins A and D) in the modulation of inflammation and injury.
研究兴趣
论文共 189 篇作者统计合作学者相似作者
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Sydney B Montesi, Christian R Gomez,Michael Beers, Robert Brown, Ishanu Chattopadhyay,Kevin R Flaherty,Christine Kim Garcia,Brigitte Gomperts,Lida P Hariri,Cory M Hogaboam,R Gisli Jenkins, Naftali Kaminski,
American journal of respiratory and critical care medicineno. 4 (2024): 362-373
Luis R Rodriguez,Konstantinos-Dionysios Alysandratos,Jeremy Katzen,Aditi Murthy, Willy Roque Barboza,Yaniv Tomer,Rebeca Acin-Perez,Anton Petcherski,Kasey Minakin, Paige Carson,Swati Iyer,Katrina Chavez,
bioRxiv : the preprint server for biology (2024)
MOLECULAR THERAPYno. 4 (2023): 266-267
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Luis R Rodriguez,Soon Yew Tang, Willy Roque Barboza,Aditi Murthy,Yaniv Tomer,Tian-Quan Cai,Swati Iyer,Katrina Chavez,Ujjalkumar Subhash Das,Soumita Ghosh, Charlotte H Cooper,Thalia T Dimopoulos,
JCI insightno. 24 (2023)
Luis Rodriguez, Swati Iyer, Katrina Chavez,Thalia Dimopoulos,Aditi Murthy, Jeremy Katzen, Surafel Mulugeta,Michael Beers
PHYSIOLOGY (2023)
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Luis R. Rodriguez,Soon Yew Tang, Willy Roque Barboza,Aditi Murthy,Yaniv Tomer,Tian-Quan Cai,Swati Iyer,Katrina Chavez,Ujjalkumar Subhash Das,Soumita Ghosh, Charlotte H. Cooper,Thalia T. Dimopoulos,
JCI INSIGHTno. 24 (2023)
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